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Exploratory Analysis of PTEN Deficiency by Immunohistochemistry from the Phas...

Jhaveri(K),Rugo(HS),Cortés(J),Oliveira(M),... Clin Cancer Res 2026-08-14

...PIK3CA/AKT1/PTEN tumor alterations. Next-generation sequencing (NGS) is commonly used to identify patients with PIK3CA/A...

Clinical factors are more strongly associated with prognosis than genetic alt...

Le(KT),Tran(HD),Do(MD),Nguyen(TH),Nguyen(T... BMC Cancer 2026-06-11

...PIK3CA mutation (p = 0.036), and co-mutation of RAS/RAF and MMR genes (p = 0.011). However, when adjusted for disease st...

PIK3CA mutation detection by circulating tumor cell sequencing guides the eff...

Zhang(J),Pei(J),Hao(G),Meng(Y),Li(F),Xu(H)... Medicine (Baltimore) 2026-05-15

...PIK3CA mutation in the patient. The patient's condition was effectively controlled after treatment with PI3K inhibitors....

Dedifferentiated/undifferentiated endometrial carcinoma:SWI/SNF-deficiency an...

Qi(Y),Yao(Q),Xu(Y),Yu(L),Tu(X),Cheng(Y),Ge... Hum Pathol 2026-09-00

...PIK3CA mutation exhibited more favorable OS (P = 0.021) and DFS (P = 0.012). Therefore, our research shows that BRG1 or ...

Survival Outcomes and Prognostic Factors in Patients with Metastatic Colorect...

Mai(NTK),Trinh(HL),Pham(AT),Nguyen(HX),Ngu... Onco Targets Ther None

...PIK3CA mutations in 9.6%. Median PFS was 14.9 months (95% CI, 10.3-19.4), and median OS was 27.0 months (95% CI, 12.4-41...

Evaluating the efficacy of Ocimum tenuiflorum as a therapeutic agent in color...

K(AH),Harishkumar(SD),Gowda(PHS),Shivamall... Front Oncol None

...PIK3CA signaling hubs central to CRC progression. Among all screened phytochemicals, rosmarinic acid demonstrated the hi...

Case Report: CLAPO syndrome: a case management and literature review.

Wang(L),Wang(M),Li(X),Jiao(B),Song(D) Front Pediatr None

...PIK3CA-related overgrowth spectrum, is a rare vascular malformation that was first reported in 2008 and formally incorpo...

A pontine-specific niche supports de novo gliomagenesis.

Pathak(A),Wells(GB),Bankaitis(VA),Xie(Z) Cell Rep 2026-08-05

...Pik3ca mutations (which co-occur with H3.1K27M in human DIPGs) induces rapid gliomagenesis specifically in the pons. We ...

Associations of TILs and genomic alterations in HER2+ early breast cancer.

Lu(S),Huang(J),Gu(Y),Wang(C),Shen(K),Fei(X... Endocr Relat Cancer 2026-08-01

...PIK3CA mutations conferred a significant DFS advantage. Integrating TIL level with PIK3CA or BRCA2 mutational status yie...

Primary Tumor Genomics and Patterns of Distant Recurrence in Resected Gastric...

Coffey(MR),Xu(J),Atri(P),Lambert(KE),Shima... JAMA Surg 2026-08-05

...PIK3CA (HR, 2.15; 95% CI, 1.25-3.69; P = .006) were independently associated with worse disease-free survival. Tumors of...

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