...PIK3CA mutation rates and higher frequency of KMT2C and FOXA1 alterations. Somatostatin receptor 2 A (SSTR2A) expression...
...PIK3CA, HRAS, and NF1. Except for TP53, the other four driver mutations are targetable. We identified three novel HER2 m...
...PIK3CA mutations, PTEN loss, and KRAS alterations. These pathways exhibit extensive crosstalk, contributing to therapeut...
...PIK3CA hotspot mutations, with ARID1A mutations were correlated with poor PFS (p < 0.001; p = 0.013). ARID1A mutation wa...
...PIK3CA, SOX2, TP53, EIF4G1, TLR7, CLDN1, PRKCI, and EPHA2. Further expansion through the PPI network identified other ta...
...PIK3CA hotspot mutation (p.E542K) and conserved oncogenic copy-number gains of PIK3CA, TERT, and MYC, as well as copy nu...
...PIK3CA, NOTCH1, and FAT1 as frequently altered genes with potential roles in penile oncogenesis. In addition, recurrent ...
...PIK3CA, HSP90AA1, STAT3] were enriched in PI3K/Akt signaling and other AD-related pathways [FDR < 0.01]. Se-PK likely mo...
...PIK3CA, and AKT1. Molecular docking and dynamics simulations showed a strong binding affinity between baicalein and PIK3...
...PIK3CA variants. Ten patients (16.9%) experienced ≥1 complication. Procedure-level complications occurred after 5/86 scl...
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