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BRCA1-like signature in triple negative breast cancer: Molecular and clinical c…

Severson(Tesa M),Peeters(Justine),Majewski(I… Mol Oncol 2016-08-15

...BRCA1-like or non-BRCA1-like. BRCA1 mutation, promoter methylation, BRCA1-like status and genome-wide expression data wa...

BRCA1-mutated estrogen receptor positive breast cancer shows BRCAness, suggesti…

Lips(Esther H),Debipersad(Rashmie),Scheerman… Clin Cancer Res 0000-00-00

...BRCA1 mutation carriers arises at an older age with less aggressive tumor characteristics than ER negative BRCA1 mutated...

Mechanisms of Therapy Resistance in Patient-Derived Xenograft Models of BRCA1-D…

Ter Brugge(Petra),Kristel(Petra),van der Bur… J Natl Cancer Inst 0000-00-00

...BRCA1-mutated and BRCA1-methylated triple-negative breast cancer.,A cohort of 75 mice carrying BRCA1-deficient breast PD...

CCDC98 targets BRCA1 to DNA damage sites.

Liu(Zixing),Wu(Jiaxue),Yu(Xiaochun) Nat Struct Mol Biol 2007-10-02

...BRCA1 translocation. Here we identify another component, CCDC98, in the BRCA1-RAP80 complex. CCDC98 mediates BRCA1's ass...

Subcellular localization of BRCA1 protein in sporadic breast carcinoma with or …

Bernard-Gallon(D J),De Latour(M P),Rio(P G),… Int J Oncol 1999-05-28

...BRCA1 and the other group of 34 breast carcinomas with no allelic loss of BRCA1. The localization of BRCA1 in the 2 grou...

Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption af…

Foray(Nicolas),Marot(Didier),Randrianarison(… Mol Cell Biol 2002-06-24

...BRCA1 and c-Abl. We show that the C terminus of BRCA1 is phosphorylated by c-Abl in vitro. In vivo, BRCA1 is phosphoryla...

BRCA1 promoter region hypermethylation in ovarian carcinoma: a population-based…

Baldwin(R L),Nemeth(E),Tran(H),Shvartsman(H)… Cancer Res 2000-10-27

...BRCA1 promoter hypermethylation demonstrated BRCA1 protein expression by immunohistochemistry. BRCA1 methylation was onl...

Identification and functional analysis of novel BRCA1 transcripts, including mo…

Pettigrew(Christopher A),French(Juliet D),Sa… Breast Cancer Res Treat 2010-02-22

...Brca1 splice variants including Brca1-Iris, the mouse orthologue of human BRCA1-IRIS. We show that Brca1-Iris is differe...

Ubiquitination and proteasomal degradation of the BRCA1 tumor suppressor is reg…

Choudhury(Atish D),Xu(Hong),Baer(Richard) J Biol Chem 2004-10-25

...BRCA1 gene can account for induction of BRCA1 expression at the G1/S transition, the mechanisms by which BRCA1 is down-r...

Posttranscriptional regulation of the breast cancer susceptibility gene BRCA1 b…

Saunus(Jodi M),French(Juliet D),Edwards(Stac… Cancer Res 2008-12-10

...BRCA1 protein expression and also BRCA1 3'UTR activity. Immunohistochemical analysis revealed that although BRCA1 and Hu...

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