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Cheng(X),Zhang(Y),Qian(C),Holdridge(E),Ana... Nat Commun 2026-05-04

...PIK3CA mutation, Trp53 loss, and MYC overexpression. Using this model together with human EC cell lines, patient-derived...

Gou(H),Li(F),Huang(Z),Zheng(J),Guo(Y),Yao(... CNS Neurol Disord Drug Targets 2026-04-24

...Pik3ca. Experimental validation demonstrated that Tet ameliorated neurological deficits and reduced cerebral ischemic da...

Srinivasan(P),Bristow(SL),Mendez(FL),Krins... Cancer Epidemiol Biomarkers... 2026-05-05

...PIK3CA between the EUR and other ancestry groups in both MSI and MSS tumors. Mutational signatures suggested enrichment ...

Yang(Y),Guo(Y),Zhu(M),Dong(Z),Jiang(S),Wen... Discov Oncol 2026-05-05

...PIK3CA. SMARCA4 mutation is an independent adverse prognostic factor in breast cancer (HR = 1.6, p = 0.02), linked to en...

Zhang(Z),Zhan(S),Tang(Y),Ling(Z),Wu(J),Rui... Hum Mutat None

...PIK3CA (8.2%) as the most frequently mutated genes. EGFR-mutant tumors exhibited significantly higher CEA levels (p = 0....

Suryavanshi(M),Ostwal(V),Javle(M),Kumar(M)... BMC Cancer 2026-04-20

...PIK3CA (9.4%). Compared to international cBioPortal data, the Indian cohort showed significantly elevated TP53 (35.8% vs...

Kumbhar(G),Suryawanshi(P),Ladke(V) Avicenna J Phytomed None

...PIK3CA, PTGS2, MAPK8, AR, TERT, PIK3CB, PARP1, and PIK3CG. Wortmannin may treat oral cancer by targeting the PI3K/AKT si...

Xu(H),Luo(R),Chen(W),Sun(Q),Chen(H),Liu(K)... Mol Carcinog 2026-07-00

...PIK3CA (18.9%). TP53 mutations were significantly enriched in left-sided colon cancers (p < 0.0001). In contrast, both K...

Zhou(F),Li(J),Zhou(Y),Zhang(X),Luo(J),Li(X... Int J Gen Med None

...PIK3CA, and PIK3R1 emerging as key targets involved in PI3K-AKT and HIF-1 signaling. SD-4 treatment significantly reduce...

Sharma(SC),Jester(A),Vidyadharan(R) Ann Plast Surg 2026-07-01

...PIK3CA-related overgrowth spectrum disorder presenting with multifocal osteolytic lesions and fractures. Diagnoses were ...