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Valerio(MR),Sambataro(D),Martorana(F),Grec... Curr Oncol 2026-03-31

...PIK3CA/AKT1/PTEN pathway is a way of overcoming resistance. Recently, the oral, selective AKT kinase inhibitor capivaser...

Yasin(I),Hang(JF),Chu(YH) Head Neck Pathol 2026-04-28

...PIK3CA, and CDKN2A mutations, with encouraging early results. This review summarizes recent progress in molecular testin...

Cao(J),Chen(Y),Song(J),Li(S),Tang(Y),Zhang... Front Oncol None

...PIK3CA-mutated HR+/HER2- advanced breast cancer, while alpelisib was the only agent to demonstrate an overall survival b...

Barron(CR),Ramineni(M),Finkelman(BS),Zhang... Hum Pathol 2026-08-00

...PIK3CA was the second most commonly mutated gene, with 27% in sporadic and 7.7% in gBRCA1 BCs (p = 0.067). Twenty-nine p...

Matsunaga(A),Ogawa(M),Kunita(A),Ikeda(Y),K... J Gynecol Oncol 2026-04-22

...PIK3CA hotspot mutations in plasma, supporting its robustness as a biomarker in liquid biopsy settings. This study highl...

Li(L),Yang(J),Xue(C),Chu(L),Zhong(H),Rao(J... Front Immunol None

...PIK3CA, AKT1, and MTOR) were analyzed. A cumulative genetic burden score was constructed by summing the number of risk a...

Bollu(V),LaGasse(K),Saucier(CD),Raymond(K)... Pediatr Blood Cancer 2026-08-00

PIK3CA-related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain-of-func...

Choschzick(M),Hoesli(L),Stergiou(C),Rüscho... Virchows Arch 2026-05-11

...PIK3CA, and CDKN2A being the most frequently altered genes. HPVA VSCCs exhibited a higher mutational burden and enrichme...

Shi(Y),Wang(X),Xi(X),Wang(M),Guo(J),Zhang(... Ther Adv Med Oncol None

...PIK3CA, ARID1A, and SMAD4, whereas ERBB2-amplified tumors showed co-gains in RARA, TOP2A, and SMARCE1. In GC, mutation-p...

Grey(GK),Muramatsu(K),Morita(Y),Ichimita(Y... J Hand Surg Asian Pac Vol 2026-06-00

...PIK3CA-related overgrowth spectrum, diagnosed typically during the paediatric age group. We present a unique case of lat...