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Yasin(I),Hang(JF),Chu(YH) Head Neck Pathol 2026-04-28

...PIK3CA, and CDKN2A mutations, with encouraging early results. This review summarizes recent progress in molecular testin...

Cao(J),Chen(Y),Song(J),Li(S),Tang(Y),Zhang... Front Oncol None

...PIK3CA-mutated HR+/HER2- advanced breast cancer, while alpelisib was the only agent to demonstrate an overall survival b...

Barron(CR),Ramineni(M),Finkelman(BS),Zhang... Hum Pathol 2026-08-00

...PIK3CA was the second most commonly mutated gene, with 27% in sporadic and 7.7% in gBRCA1 BCs (p = 0.067). Twenty-nine p...

Marchetti(P),Curigliano(G),Westphalen(CB),... NPJ Precis Oncol 2026-04-10

...PIK3CA/AKT/PTEN pathway. Exclusions were mainly due to a lack of actionable alterations or unavailable trial drugs. The ...

Sadeghi(H),Seif(F) Biochem Genet 2026-04-11

...PIK3CA regulatory regions. Triple-positive patients (mutations in all 3 regions) had significantly worse progression-fre...

Mugundan(UM),Saravanan(V),Ganesan(RM) Sci Rep 2026-04-11

...PIK3CA) involved in PI3K/AKT, MAPK, ErbB, and HIF-1 signaling were highlighted among the 142 shared targets between Valg...

Lin(R),Chen(R),Tao(L),Jiang(X),Yu(F) J Ethnopharmacol 2026-08-10

...PIK3CA, and AKT1), which were notably enriched in the PI3K-Akt signaling pathway among others. In vivo, DLC dose-depende...

Fraissenon(A),Kugusheva(A),Ladraa(S),Guiba... Comput Methods Programs Biomed 2026-07-00

Venous malformations (VM), commonly observed in PIK3CA-related overgrowth spectrum (PROS), are infiltrative and widely d...

Ye(D),Zhao(Y),Yang(L),Sun(X),Cao(T),Yuan(M... Clin Genitourin Cancer 2026-06-00

...PIK3CA, and BRCA1/2 mutations in ctDNA were linked to inferior PFS, whereas BRCA1/2 mutations did not significantly wors...

Juric(D),Rugo(HS),Reising(A),Vervier(K),Ma... Ann Oncol 2026-08-00

...PIK3CA-altered cohort. PIK3CA-altered and PIK3CA-wild type tumors had distinct genomic profiles. In the PIK3CA-altered c...