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A Comparison of Fresh Frozen vs. Formalin-Fixed, Paraffin-Embedded Specimens ...

Lüder Ripoli(Florenza),Mohr(Annika),Conrad... Int J Mol Sci 0000-00-00

...Pik3ca; Mcl1; MAPK3; FOXO3; PTEN; GATA4; PFDN5; HMGB1; MAPK1; BRCA2; BRCA1; HMGA2; and Her2) were analyzed via branched-...

A Phase II Study of Poziotinib in Patients with Epidermal Growth Factor Recep...

Han(Ji-Youn),Lee(Ki Hyeong),Kim(Sang-We),M... Cancer Res Treat 0000-00-00

...PIK3CA mutations were detected in the prestudy tumors, and seven T790M mutations were detected in the plasma assay. Thre...

Tumour CD274 (PD-L1) expression and T cells in colorectal cancer.

Masugi(Yohei),Nishihara(Reiko),Yang(Juhong... Gut 0000-00-00

...PIK3CA mutations.,CD274 expression in tumour cells or stromal cells (including immune cells) was detected in 731 (89%) o...

Molecular Insights of Pathways Resulting from Two Common PIK3CA Mutations in ...

Bhat-Nakshatri(Poornima),Goswami(Chirayu P... Cancer Res 0000-00-00

...PIK3CA mutations and/or PI3K hyperactivation, we show that PIK3CA-E545K mutations (found in ∼20% of PIK3CA-mutant breast...

Personalized medicine in a phase I clinical trials program: The M. D. Anderso...

Tsimberidou(A M),Iskander(N G),Hong(D S),W... J Clin Oncol 0000-00-00

...PIK3CA mutation; 19% KRAS; 8% NRAS; 19% BRAF; 3% EGFR; and 2% had a CKIT mutation; 21% had PTEN loss. Results are shown ...

Identification of driver mutations in tumor specimens from 1,000 patients wit...

Kris(M G),Johnson(B E),Kwiatkowski(D J),Ia... J Clin Oncol 0000-00-00

...PIK3CA, AKT1, MEK1, and NRAS using standard multiplexed assays and fluorescence in situ hybridization (FISH) for ALK rea...

Somatic overgrowth disorders of the PI3K/AKT/mTOR pathway & therapeutic strat...

Keppler-Noreuil(Kim M),Parker(Victoria E R... Am J Med Genet C Semin Med ... 0000-00-00

...PIK3CA-Related Overgrowth Spectrum, Proteus syndrome, and brain overgrowth conditions. Clinical findings in these disord...

Enumeration and targeted analysis of KRAS, BRAF and PIK3CA mutations in CTCs ...

Kidess-Sigal(Evelyn),Liu(Haiyan E),Triboul... Oncotarget 0000-00-00

...PIK3CA hotspot mutations were analyzed in CTCs and ctDNA from 23 samples, nine matched liver metastases and three primar...

Genomic landscape of small cell carcinoma of the breast contrasted to small c...

McCullar(Brennan),Pandey(Manjari),Yaghmour... Breast Cancer Res Treat 0000-00-00

...PIK3CA, and TOP2A, and next generation sequencing as well as Sanger sequencing of 47 genes. 19 patients with small cell ...

Identification of new candidate therapeutic target genes in head and neck squ...

Sablin(Marie-Paule),Dubot(Coraline),Klijan... Oncotarget 0000-00-00

...PIK3CA expression was an independent prognostic marker, associated with shorter disease-free survival.,We identified dru...

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