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Mosaic Disorders of the PI3K/PTEN/AKT/TSC/mTORC1 Signaling Pathway.

Nathan(Neera),Keppler-Noreuil(Kim M),Biese... Dermatol Clin 0000-00-00

...PIK3CA cause Proteus syndrome and PIK3CA-Related Overgrowth Spectrum, respectively. Postzygotic mutations in PTEN or TSC...

The High Frequency of PIK3CA Mutations in Iranian Breast Cancer Patients.

Azizi Tabesh(Ghasem),Izadi(Pantea),Fereido... Cancer Invest 0000-00-00

...PIK3CA oncogene are common. We investigated the mutational status of exons 9 and 20 of the PIK3CA gene by polymerase cha...

Amplification of USP13 drives ovarian cancer metabolism.

Han(Cecil),Yang(Lifeng),Choi(Hyun Ho),Badd... Nat Commun 0000-00-00

...PIK3CA in 29.3% of high-grade serous ovarian cancers and its overexpression is significantly associated with poor clinic...

A phase IB study of AMG 479, a type 1 insulin-like growth factor receptor (IG...

Sarantopoulos(J),Mita(A C),Mulay(M),Romero... J Clin Oncol 0000-00-00

...PIK3CA & RAS mutation) will be presented. [Table: see text] [Table: see text].

Distinct PIK3CA mutation profiles in estrogen receptor (ER) negative breast c...

Doane(A S),Danso(M),Lal(P),Donaton(M),Whel... J Clin Oncol 0000-00-00

...PIK3CA exons 9 and 20 were sequenced by RT-PCR amplification, direct sequencing, and restriction enzyme digest.,Genes di...

PIK3CA as a molecular target in mantle cell lymphoma.

Papageorgiou(S),Psyrri(A),Liakata(E),Scori... J Clin Oncol 0000-00-00

...PIK3CA gene copy number. PIK3CA gene mutations were not identified. In addition, amplification of PIK3CA correlated with...

PIK3CA mutations in breast cancer: A potential predictive marker.

Santarpia(M),Altavilla(G),Margeli(M),Mesit... J Clin Oncol 0000-00-00

639 Background: Somatic mutations in phosphoinositide-3-kinase catalytic alpha (PIK3CA) activates Akt, attenuates apopto...

Mutational profiling of protein kinases in prostate carcinoma.

Andea(A),Osman(I),Scardino(P),Scher(H),Ger... J Clin Oncol 0000-00-00

...PIK3CA). We also sequenced PTEN, p53 and AR because of their known association with prostate cancer and interactions wit...

Genetic study of congenital bile-duct dilatation identifies de novo and inher...

Wong(John K L),Campbell(Desmond),Ngo(Ngoc ... BMC Med Genomics 0000-00-00

...PIK3CA, TLN1 CYLD, MAP2K1). Importantly, CDD patients have an excess of DNVs in cancer-related genes (p < 0.025). Thirte...

PIK3CA, BCL-6, MLL and FOXP1 in the transformation and prognosis of MALT lymp...

Zhai(L Z),Huang(Y),Wang(S S),Cao(Y B),Xiao... J Clin Oncol 0000-00-00

...PIK3CA, BCL-6, MLL and FOXP1. Rare studies about the role of expression of 4 oncogenes in the transformation and prognos...

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