...PIK3CA in 29.3% of high-grade serous ovarian cancers and its overexpression is significantly associated with poor clinic...
...PIK3CA and FBXW7 that are also mutated in other HPV-associated cancers. Overall mutational burden was not significantly ...
...PIK3CA, TP53, CDH1, MLL3, ABCA13 and FLG with 71% concordance between paired cores. TP53 mutations are associated with p...
...PIK3CA, MYCL and SRC genes were found at rates similar to carcinomas, while MEN1 loss rate mirrored that of TCs. Multiva...
...PIK3CA mutations occurs frequently in human cancers but targeting Akt has been difficult due to the mechanism-based toxi...
...PIK3CA, PTEN and EGFR), endocytosis (e.g., the PDGFRA, SMAD2, ERBB3, PML and FGFR2), and the cell cycle (e.g., SMAD2, CC...
...PIK3CA in twenty-five patients during a 2-y period. A total of 2,178 cfDNA mutation analyses were performed and we obser...
...PIK3CA mutation, BRCA2 mutation, ERBB2 amplification, and CCND1 amplification. In total, 22% of the analyzed patients co...
...PIK3CA hotspot mutations were analyzed in CTCs and ctDNA from 23 samples, nine matched liver metastases and three primar...
...PIK3CA mutations followed by a keratinizing carcinoma with mutations in both PIK3CA and TP53. This study, for the first ...
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