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Combined inhibition of PI3K and PARP is effective in the treatment of ovarian...

Wang(Dong),Li(Chengbo),Zhang(Yuan),Wang(Mi... Gynecol Oncol 0000-00-00

...PIK3CA genes.,We exposed three wild-type PIK3CA ovarian cancer cell lines to a PI3K inhibitor BKM120 and/or a PARP inhib...

CLOVES syndrome: review of a PIK3CA-related overgrowth spectrum (PROS).

Martinez-Lopez(A),Blasco-Morente(G),Perez-... Clin Genet 0000-00-00

...PIK3CA has been proposed, designated PIK3CA-related overgrowth spectrum (PROS), with the aim of facilitating clinical ma...

Causal Mechanistic Regulatory Network for Glioblastoma Deciphered Using Syste...

Plaisier(Christopher L),O'Brien(Sofie),Ber... Cell Syst 0000-00-00

...PIK3CA modulate IRF1-mediated regulation of MHC class I antigen processing and presentation genes to increase tumor lymp...

"Wild type" GIST: Clinicopathological features and clinical practice.

Wada(Ryuichi),Arai(Hiroki),Kure(Shoko),Pen... Pathol Int 0000-00-00

...PIK3CA and with the ETV6-NTRK3 fusion gene. GIST in NF occurs in the small intestine, and tumor cells are spindle shaped...

Tumor LINE-1 methylation level and colorectal cancer location in relation to ...

Mima(Kosuke),Nowak(Jonathan A),Qian(Zhi Ro... Oncotarget 0000-00-00

...PIK3CA mutations. A statistically significant interaction was found between LINE-1 methylation level and tumor location ...

Targeting mTOR pathway inhibits tumor growth in different molecular subtypes ...

Hatem(Rana),El Botty(Rania),Chateau-Jouber... Oncotarget 0000-00-00

...PIK3CA and AKT1 genes were rare. In 7 PDX treatment with everolimus resulted in a tumor growth inhibition higher than 50...

A proportion of primary squamous cell carcinomas of the parotid gland harbour...

Xu(Bin),Wang(Lu),Borsu(Laetitia),Ghossein(... Histopathology 0000-00-00

...PIK3CA, AKT1, MEK1 and ERBB2), and studied by fluorescence in-situ hybridization for PTEN copy number alteration. Three ...

Prognostic and clinical impact of PIK3CA mutation in gastric cancer: pyrosequ...

Harada(Kazuto),Baba(Yoshifumi),Shigaki(Hir... BMC Cancer 0000-00-00

...PIK3CA mutations in gastric cancer remains unclear. This retrospective study investigated the relationship between PIK3C...

Landscape of Phosphatidylinositol-3-Kinase Pathway Alterations Across 19 784 ...

Millis(Sherri Z),Ikeda(Sadakatsu),Reddy(Sa... JAMA Oncol 0000-00-00

...PIK3CA mutations in endometrial (37%), breast (31%), cervical (29%), and anal cancer (27%). PIK3CA, PTEN, and AKT1 mutat...

CpG island methylator phenotype is associated with the efficacy of sequential...

Zhang(Xiaofei),Shimodaira(Hideki),Soeda(Hi... Int J Clin Oncol 0000-00-00

...PIK3CA, NRAS, and AKT1) as detected by direct sequencing.,CIMP-positive status was significantly associated with proxima...

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