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Chromatin remodeling gene AT-rich interactive domain-containing protein 1A su...

Zhang(Qian),Yan(Hai-Bo),Wang(Jie),Cui(Shu-... Oncotarget 0000-00-00

...PIK3CA and PDK1 transcription by direct binding to their promoters. Serial deletion mutation analyses revealed that the ...

Genomic Landscape of poorly Differentiated and Anaplastic Thyroid Carcinoma.

Xu(Bin),Ghossein(Ronald) Endocr Pathol 0000-00-00

...PIK3CA-PTEN-AKT-mTOR pathway, SWI-SNF complex, histomethyltransferases, and mismatch repair genes. RAS-mutated PDTCs are...

Mutation profiling in chinese patients with metastatic colorectal cancer and ...

Li(Zhe-Zhen),Wang(Feng),Zhang(Zi-Chen),Wan... Oncotarget 0000-00-00

...PIK3CA (9.6%), NRAS (4.3%), BRAF (3.4%), EGFR (2.5%) and HRAS (1.2%). Less frequent mutations were detected in PDGFRA, R...

Genetically-defined novel oral squamous cell carcinoma cell lines for the dev...

Fadlullah(Muhammad Zaki Hidayatullah),Chia... Oncotarget 0000-00-00

...PIK3CA. Notably, we identified mutations (MLL4, USP9X, ARID2) in cell lines derived from betel quid users that may be as...

Deciphering intra-tumor heterogeneity of lung adenocarcinoma confirms that do...

Pelosi(Giuseppe),Pellegrinelli(Alessio),Fa... Virchows Arch 0000-00-00

...PIK3CA, TP53, and EGFR exon 18) occurred in two or more regions, while private mutations (in ABL1, ALK, BRAF, HER2, KDR,...

Triggering PIK3CA mutations in PI3K/AKT/mTOR axis: Exploration of newer inhib...

Asati(Vivek),Bharti(Sanjay K),Mahapatra(De... Curr Pharm Des 0000-00-00

...PIK3CA mutations discussed as a major target for various cancers. These PIK3CA mutations were found in various exon incl...

Utility of clinical high-depth next generation sequencing for somatic variant...

Hucthagowder(V),Shenoy(A),Corliss(M),Vigh-... Clin Genet 0000-00-00

...PIK3CA, has been described in somatic overgrowth syndromes and vascular malformations. Detection of PIK3CA somatic alter...

Influence maximization in time bounded network identifies transcription facto...

Jo(Kyuri),Jung(Inuk),Moon(Ji Hwan),Kim(Sun... Bioinformatics 0000-00-00

...PIK3CA knock-in dataset and found significant sub-pathways and their regulators relevant to the PIP3 signaling pathway.,...

MARCH2 regulates autophagy by promoting CFTR ubiquitination and degradation a...

Xia(Dan),Qu(Liujing),Li(Ge),Hongdu(Beiqi),... Autophagy 0000-00-00

...PIK3CA-AKT-MTOR signaling pathway. Additionally, we found that MARCH2 interacts with CFTR (cystic fibrosis transmembrane...

PI3K/AKT Signaling Regulates H3K4 Methylation in Breast Cancer.

Spangle(Jennifer M),Dreijerink(Koen M),Gro... Cell Rep 0000-00-00

...PIK3CA allele and that inhibition of PI3K/AKT signaling reduces promoter-associated H3K4me3 in human breast cancer cells...

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