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Maternal and fetal genomes interplay through phosphoinositol 3-kinase(PI3K)-p...

Sferruzzi-Perri(Amanda N),López-Tello(Jorg... Proc Natl Acad Sci U S A 0000-00-00

...Pik3ca (encoding PIK3CA also known as p110α, α/+), we examined the interplay between the maternal genome and the fetal g...

MYOD1 (L122R) mutations are associated with spindle cell and sclerosing rhabd...

Rekhi(Bharat),Upadhyay(Pawan),Ramteke(Mano... Mod Pathol 0000-00-00

...PIK3CA (H1047), and PIK3CA (E542/E545) mutations, along with immunohistochemical analysis of desmin, myogenin, and MYOD1...

Specific inhibition of p110α subunit of PI3K: putative therapeutic strategy f...

Fernandes(Maria Sofia),Melo(Soraia),Velho(... Oncotarget 0000-00-00

...PIK3CA mutations or KRAS mutations alone. Specific silencing of PI3K p110α by small interfering RNA (siRNA) reduced viab...

ctDNA dynamics: a novel indicator to track resistance in metastatic breast ca...

Ma(Fei),Zhu(Wenjie),Guan(Yanfang),Yang(Lin... Oncotarget 0000-00-00

...PIK3CA/MTOR/PTEN. Compared with CT scans, dynamic ctDNA profiling utilizing pre-defined criteria was sensitive in identi...

MiR-155 promotes epithelial-mesenchymal transition in hepatocellular carcinom...

Kong(Xin),Liu(Fengchao),Gao(Jian) Oncotarget 0000-00-00

...PIK3CA, the gene encoding the catalytic subunit of phosphoinositide 3-kinase (PI3K), occur with high frequency in hepato...

A multicenter, single-arm, open-label, phase 2 study of apitolisib (GDC-0980)...

Makker(Vicky),Recio(Fernando O),Ma(Ling),M... Cancer 0000-00-00

...PIK3CA), phosphatase and tensin homolog (PTEN), or AKT1. All 3 patients with a confirmed response had at least 1 alterat...

Detection of multiple mutations in urinary exfoliated cells from male bladder...

Critelli(Rossana),Fasanelli(Francesca),Ode... Oncotarget 0000-00-00

...PIK3CA, and RAS genes have been proposed as potential molecular markers in bladder tumor. Their concomitant presence in ...

Mechanisms of resistance to anti-epidermal growth factor receptor inhibitors ...

Sforza(Vincenzo),Martinelli(Erika),Ciardie... World J Gastroenterol 0000-00-00

...PIK3CA-AKT pathways. In this review, we describe the currently known mechanisms of primary and acquired resistance to an...

Systematic Functional Characterization of Resistance to PI3K Inhibition in Br...

Le(Xiuning),Antony(Rajee),Razavi(Pedram),T... Cancer Discov 0000-00-00

PIK3CA (which encodes the PI3K alpha isoform) is the most frequently mutated oncogene in breast cancer. Small-molecule P...

Genetic basis for vascular anomalies.

Kirkorian(A Yasmine),Grossberg(Anna L),Püt... Semin Cutan Med Surg 0000-00-00

...PIK3CA-related overgrowth spectrum (PROS), Proteus syndrome, SOLAMEN syndrome, Sturge-Weber syndrome, phakomatosis pigme...

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