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Molecular differences in the microsatellite stable phenotype between left-sid...

Takahashi(Yayoi),Sugai(Tamotsu),Habano(Wat... Int J Cancer 0000-00-00

...PIK3CA genes were examined using PCR-bisulfite pyrosequencing (for KRAS and BRAF mutations) or PCR-single conformation p...

PIK3CA dependence and sensitivity to therapeutic targeting in urothelial carc...

Ross(R L),McPherson(H R),Kettlewell(L),Shn... BMC Cancer 0000-00-00

...PIK3CA mutations. Sensitivity to GDC-0941 was dependent on hotspot PIK3CA mutation status. Cells with rare PIK3CA mutati...

Frequent detection of PIK3CA mutations in single circulating tumor cells of p...

Gasch(Christin),Oldopp(Theresa),Mauermann(... Mol Oncol 0000-00-00

...PIK3CA mutations. Detection and characterization of HER2 expression of CTC were conducted with the CellSearch(®) system....

LRG1 mRNA expression in breast cancer associates with PIK3CA genotype and wit...

Ramirez-Ardila(Diana E),Ruigrok-Ritstier(K... Mol Oncol 0000-00-00

...PIK3CA status in both datasets. All except miR-301a-3p had an increased expression in tumors with PIK3CA mutations. Vali...

Phosphatidyl inositol-3 kinase (PIK3CA) E545K mutation confers cisplatin resi...

Arjumand(Wani),Merry(Cole D),Wang(Chen),Sa... Oncotarget 0000-00-00

...PIK3CA or with PIK3CA depleted. Cells expressing the PIK3CA-E545K mutation also had constitutive PI3K pathway activation...

Integrated molecular pathway analysis informs a synergistic combination thera...

She(Qing-Bai),Gruvberger-Saal(Sofia K),Mau... BMC Cancer 0000-00-00

...PIK3CA, PTEN, or INPP4B; when including upstream kinases HER2 and EGFR, 75 % of cases had one or more aberration includi...

Relationship between tumor biomarkers and efficacy in TH3RESA, a phase III st...

Kim(Sung-Bae),Wildiers(Hans),Krop(Ian E),S... Int J Cancer 0000-00-00

...PIK3CA and PTEN subgroups. Consistent with other reports, benefit was seen with T-DM1 regardless of PIK3CA mutation stat...

Pro-survival responses to the dual inhibition of anti-apoptotic Bcl-2 family ...

Risberg(Karianne),Redalen(Kathrine Røe),Sø... BMC Cancer 0000-00-00

...PIK3CA mutation), BRAF/PIK3CA-mutant RKO, and wild-type Colo320DM cell lines (all with high endogenous Mcl-1 expression ...

Genomic characterization of recurrent high-grade astroblastoma.

Bale(Tejus A),Abedalthagafi(Malak),Bi(Weny... Cancer Genet 0000-00-00

...PIK3CA(R38H) and ERG(A403T)). Conversely, another case, originally classified as glioblastoma with nine-year survival be...

Combined inhibition of PI3K and PARP is effective in the treatment of ovarian...

Wang(Dong),Li(Chengbo),Zhang(Yuan),Wang(Mi... Gynecol Oncol 0000-00-00

...PIK3CA genes.,We exposed three wild-type PIK3CA ovarian cancer cell lines to a PI3K inhibitor BKM120 and/or a PARP inhib...

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