...PIK3CA, and TP53 We further showed that cmDetect detected ctDNA in 89% of patients with confirmed mutated cell-free tumo...
...PIK3CA were overexpressed in the pemetrexed-resistant pancreatic cancer cell line. PTEN and PIK3CA were shown to be upre...
...Pik3ca), low-grade serous carcinoma (Braf), endometrioid (Ctnnb1), or mucinous (Kras) carcinomas. Using CRISPR/Cas9 gene...
...PIK3CA, HRAS, CDK4, FBXW7 and RB1. Mutational co-occurrence predominantly existed between TP53 and PIK3CA, TP53 and CDKN...
...PIK3CA mutations, were also reported. However, the mechanisms in the remaining patients are still unknown. In this study...
...PIK3CA, ALK, and PTEN as well as variants at COSMIC annotated sites in all six patients analyzed. Moreover, cfDNA reveal...
...PIK3CA), our data establish a potential mechanistic link between AGGF1 and PIK3CA, the two genes identified for KTS.
...PIK3CA were frequently comutated. We identified no association between mutations in specific genes and key clinical outc...
...PIK3CA mutations, could provide trastuzumab resistance in GEA.,Expression of HER2 and PTEN, and PIK3CA gene mutations we...
...PIK3CA, TP53) and 460 non-recurrent variants. The tumors/metastases concordance of variants was 75%, higher for recurren...
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