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Utility of clinical high-depth next generation sequencing for somatic variant...

Hucthagowder(V),Shenoy(A),Corliss(M),Vigh-... Clin Genet 0000-00-00

...PIK3CA, has been described in somatic overgrowth syndromes and vascular malformations. Detection of PIK3CA somatic alter...

Influence maximization in time bounded network identifies transcription facto...

Jo(Kyuri),Jung(Inuk),Moon(Ji Hwan),Kim(Sun... Bioinformatics 0000-00-00

...PIK3CA knock-in dataset and found significant sub-pathways and their regulators relevant to the PIP3 signaling pathway.,...

Distinctive Patterns of CTNNB1 (β-Catenin) Alterations in Salivary Gland Basa...

Jo(Vickie Y),Sholl(Lynette M),Krane(Jeffre... Am J Surg Pathol 0000-00-00

...PIK3CA, biallelic inactivation of NFKBIA, focal CYLD deletion, and without CTNNB1 mutation despite focal β-catenin expre...

MARCH2 regulates autophagy by promoting CFTR ubiquitination and degradation a...

Xia(Dan),Qu(Liujing),Li(Ge),Hongdu(Beiqi),... Autophagy 0000-00-00

...PIK3CA-AKT-MTOR signaling pathway. Additionally, we found that MARCH2 interacts with CFTR (cystic fibrosis transmembrane...

PI3K/AKT Signaling Regulates H3K4 Methylation in Breast Cancer.

Spangle(Jennifer M),Dreijerink(Koen M),Gro... Cell Rep 0000-00-00

...PIK3CA allele and that inhibition of PI3K/AKT signaling reduces promoter-associated H3K4me3 in human breast cancer cells...

The role of aspirin in colorectal cancer chemoprevention.

Singh Ranger(Gurpreet) Crit Rev Oncol Hematol 0000-00-00

...PIK3CA pathway, or therapy-induced senescence of cancer cells. The most serious side effect of prolonged aspirin treatme...

Suppression of SPIN1-mediated PI3K-Akt pathway by miR-489 increases chemosens...

Chen(Xu),Wang(Ya-Wen),Xing(Ai-Yan),Xiang(S... J Pathol 0000-00-00

...PIK3CA, AKT, CREB1 and BCL2 in the PI3K-Akt signalling pathway, demonstrated to be elevated in drug-resistant breast can...

Assessment of the clinical application of detecting EGFR, KRAS, PIK3CA and BR...

Xu(Xinnan),Yang(Yang),Li(Hui),Chen(Zhao),J... Scand J Clin Lab Invest 0000-00-00

...PIK3CA and BRAF. Discordant variants were further validated by Sanger sequencing and independent qPCR and NGS assays.,Ou...

Prognostic factors in the myoepithelial-like spindle cell type of metaplastic...

Leo(Fabian),Bartels(Stephan),Mägel(Lavinia... Virchows Arch 0000-00-00

...PIK3CA, PTEN, SF3B1, SMAD4, SRC, SRSF2, STK11, TP53, and U2AF1; copy numbers for EGFR, c-myc, FGFR, PLAG, c-met) were as...

Mutational analysis of anal cancers demonstrates frequent PIK3CA mutations as...

Cacheux(Wulfran),Rouleau(Etienne),Briaux(A... Br J Cancer 0000-00-00

...PIK3CA mutation (P=0.037). The PIK3CA status retained its prognostic significance in Cox multivariate regression analysi...

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