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Lobular breast cancer: Clinical, molecular and morphological characteristics.

Christgen(Matthias),Steinemann(Doris),Kühn... Pathol Res Pract 0000-00-00

...PIK3CA, TP53, FOXA1, FGFR1, ZNF703 and BCAR4, have been implicated in ILBC or progression of lobular carcinoma in situ (...

MYC copy gain, chromosomal instability and PI3K activation as potential marke...

Gogas(Helen),Kotoula(Vassiliki),Alexopoulo... J Transl Med 0000-00-00

...PIK3CA mutations; PTEN and phospho-mTOR protein expression). Increased CEN CN was assessed based on normal cut-offs. Tim...

Frequent PIK3CA-activating mutations in hidradenoma papilliferums.

Liau(Jau-Yu),Lan(Jui),Hong(Jin-Bon),Tsai(J... Hum Pathol 0000-00-00

...PIK3CA or AKT1, with each gene accounting for 30% of cases. In this study, we screened the mutation statuses of PIK3CA, ...

ICECREAM: randomised phase II study of cetuximab alone or in combination with...

Segelov(Eva),Waring(Paul),Desai(Jayesh),Wi... BMC Cancer 0000-00-00

...PIK3CA predicts response to EFGR-inhibitors. The ICECREAM trial examines the question of monotherapy versus combination ...

Assessment of the clinical application of detecting EGFR, KRAS, PIK3CA and BR...

Xu(Xinnan),Yang(Yang),Li(Hui),Chen(Zhao),J... Scand J Clin Lab Invest 0000-00-00

...PIK3CA and BRAF. Discordant variants were further validated by Sanger sequencing and independent qPCR and NGS assays.,Ou...

Prognostic factors in the myoepithelial-like spindle cell type of metaplastic...

Leo(Fabian),Bartels(Stephan),Mägel(Lavinia... Virchows Arch 0000-00-00

...PIK3CA, PTEN, SF3B1, SMAD4, SRC, SRSF2, STK11, TP53, and U2AF1; copy numbers for EGFR, c-myc, FGFR, PLAG, c-met) were as...

Mutational analysis of anal cancers demonstrates frequent PIK3CA mutations as...

Cacheux(Wulfran),Rouleau(Etienne),Briaux(A... Br J Cancer 0000-00-00

...PIK3CA mutation (P=0.037). The PIK3CA status retained its prognostic significance in Cox multivariate regression analysi...

Use of Liquid Biopsies in Clinical Oncology: Pilot Experience in 168 Patients...

Schwaederle(Maria),Husain(Hatim),Fanta(Pau... Clin Cancer Res 0000-00-00

...PIK3CA, and 93.1% for ERBB2 alterations. There was a significant correlation between the cases with ≥ 1 alteration with ...

Clinicopathogenomic analysis of mismatch repair proficient colorectal adenoca...

Braxton(David R),Zhang(Ray),Morrissette(Je... Int J Cancer 0000-00-00

...PIK3CA mutations. Hierarchical clustering revealed a TP53 mutant subtype and a MAPK-PIK3CA subtype with differing patter...

A Comparative Analysis of Genetic and Epigenetic Events of Breast and Ovarian...

Longacre(Mckenna),Snyder(Nicole A),Housman... Int J Mol Sci 0000-00-00

...PIK3CA; down regulation of miRNAs 9, 100, 125a, 125b, and 214; and epigenetic alterations such as H3K27me3, H3K9me2, H3K...

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