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Combination Therapy with AKT3 and PI3KCA siRNA Enhances the Antitumor Effect ...

Paul-Samojedny(Monika),Pudełko(Adam),Kowal... BioDrugs 0000-00-00

...PIK3CA genes on the susceptibility of T98G cells to temozolomide (TMZ) and carmustine (BCNU).,T98G cells were transfecte...

Determination of somatic oncogenic mutations linked to target-based therapies...

Ibarrola-Villava(Maider),Fleitas(Tania),Ll... Oncotarget 0000-00-00

...PIK3CA were detected in 40/97 (41.2%) and 30/97 (30.9%) patients respectively. Thirty-one patients (32.0%) had mutations...

Mutational status of synchronous and metachronous tumor samples in patients w...

Quéré(Gilles),Descourt(Renaud),Robinet(Gil... BMC Cancer 0000-00-00

...PIK3CA, HER2) in patients with metastatic non-small-cell lung cancer for whom two tumor samples were available.,A retros...

The clinical value of HER-2 overexpression and PIK3CA mutations in the older ...

Engels(Charla C),Kiderlen(Mandy),Bastiaann... Breast Cancer Res Treat 0000-00-00

...PIK3CA mutations in older breast cancer patients. Female breast cancer patients aged 65 years or older, diagnosed betwee...

Molecular mechanisms mediating the beneficial metabolic effects of [Arg4]tige...

Ojo(Opeolu O),Srinivasan(Dinesh K),Owolabi... Biol Chem 0000-00-00

...Pik3ca, and Slc2a4). These observations encourage further development of tigerinin-1R analogues for the treatment of pat...

Phase II Study of a Non-Platinum-Containing Doublet of Paclitaxel and Pemetre...

Pietanza(M C),Hellmann(Matthew D),Fiore(Jo... J Thorac Oncol 0000-00-00

...PIK3CA), one; epidermal growth factor receptor gene (EGFR) exon 20 insertion, one; and driver 15, none. A total of 23 pa...

The Genomic Landscape of Male Breast Cancers.

Piscuoglio(Salvatore),Ng(Charlotte K Y),Mu... Clin Cancer Res 0000-00-00

...PIK3CA (20%) and GATA3 (15%). ER-positive/HER2-negative male breast cancers, however, less frequently harbored 16q losse...

Establishment and characterization of a novel ovarian clear cell carcinoma ce...

Sato(Seiya),Itamochi(Hiroaki),Oumi(Nao),Ch... Hum Cell 0000-00-00

...PIK3CA in exons 9 and 20 and of TP53 in exons 4-9. We observed the loss of ARID1A protein expression in TU-OC-2 cells by...

Comprehensive molecular portrait using next generation sequencing of resected...

Bria(E),Pilotto(S),Simbolo(M),Fassan(M),de... Sci Rep 0000-00-00

...PIK3CA (29.4%), KRAS (26.5%), TP53 (26.5%) MET (8.8%), SMAD4 (8.8%) and STK11 (8.8%). Multiple gene mutations were found...

Value of KRAS, BRAF, and PIK3CA Mutations and Survival Benefit from Systemic ...

Sasaki(Yusuke),Hamaguchi(Tetsuya),Yamada(Y... Asian Pac J Cancer Prev 0000-00-00

...PIK3CA gene mutations, and overall survival (OS) were compared between the two groups.,The median OS values were 23.3 an...

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