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Bogani(G),Moore(KN),Ray-Coquard(I),Ceccaro... Gynecol Oncol 2026-06-00

...PIK3CA, and PTEN, alongside epigenetic changes and dysregulation of inflammatory and estrogen-dependent pathways, suppor...

van den Ende(NS),Smid(M),Martens(JWM),Debe... NPJ Breast Cancer 2026-05-13

...PIK3CA, and RB1, have been associated with favorable responses to targeted therapeutics in clinical trials. Moreover, 20...

Van Dinh(L),Nguyen(NBT),Vu(TQ),Dang(HH),Ng... BMC Cancer 2026-05-12

...PIK3CA (20%), ALK (14%), and KRAS (9%). Multivariate analysis suggested patients with EGFR dual mutations were correlate...

Liu(J),Zheng(J),Wu(J),Sun(Y),Huang(M),Su(J... Foods 2026-04-27

...PIK3CA, PIK3CB, and ALOX15). GO and KEGG enrichment analyses indicated that these targets participated in diverse biolog...

Pellegrino(F),Reynolds(G),Cardaropoli(S),L... Cells 2026-04-27

Background: PIK3CA-related overgrowth spectrum (PROS) comprises a heterogeneous group of mosaic disorders caused by acti...

De Marco(C),Rocca(V),Migliozzi(S),Venezian... Cancers (Basel) 2026-04-28

...PIK3CA, and TET1. Mutations in these genes were associated with reduced overall survival in exploratory analyses (median...

Gauduchon(T),Digue(L),Ferlay(C),Treilleux(... Oral Oncol 2026-07-00

...PIK3CA wild-type, n = 36; PIK3CA-mutated, n = 22); 78% had received ≥ 2 prior lines of systemic therapy. The PIK3CA-muta...

Zhang(T),Wang(J),Li(J),Liang(Y),Tang(S),Hu... Fitoterapia 2026-07-00

...PIK3CA, MAPK8, and BCL2L1 as core targets of YQHXF. YQHXF upregulated miR-29b-3p, downregulated PTEN, and activated PI3K...

Marchiò(C),Rojo(F),Copson(ER),Schmitt(F),B... NPJ Breast Cancer 2026-05-15

PIK3CA mutations are common in HR+/HER2- metastatic breast cancer and guide the use of PI3K-targeted therapies. This exp...

Hayashi(H),Cho(BC),Spigel(DR),Girard(N),Le... J Thorac Oncol 2026-04-28

...PIK3CA, RASorRAF, cell cycle, TP53orRB1 loss-of-function) resistance; absence of these detectable alterations constitute...