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Genetically-defined novel oral squamous cell carcinoma cell lines for the dev...

Fadlullah(Muhammad Zaki Hidayatullah),Chia... Oncotarget 0000-00-00

...PIK3CA. Notably, we identified mutations (MLL4, USP9X, ARID2) in cell lines derived from betel quid users that may be as...

Deciphering intra-tumor heterogeneity of lung adenocarcinoma confirms that do...

Pelosi(Giuseppe),Pellegrinelli(Alessio),Fa... Virchows Arch 0000-00-00

...PIK3CA, TP53, and EGFR exon 18) occurred in two or more regions, while private mutations (in ABL1, ALK, BRAF, HER2, KDR,...

Cetuximab continuation after first progression in metastatic colorectal cance...

Ciardiello(F),Normanno(N),Martinelli(E),Tr... Ann Oncol 0000-00-00

...PIK3CA wild-type tumours. For these patients, PFS was longer in the FOLFOX plus cetuximab arm [median 6.9 (95% CI 5.5-8....

Mutations of KRAS/NRAS/BRAF predict cetuximab resistance in metastatic colore...

Hsu(Hung-Chih),Thiam(Tan Kien),Lu(Yen-Jung... Oncotarget 0000-00-00

...PIK3CA, KRAS (exons 3 and 4), NRAS, PTEN, and AKT1 mutations were detected in 6, 6, 5, 4, 1, and 1 patient, respectively...

EGFR, COX2, p-AKT expression and PIK3CA mutation in distal extrahepatic bile ...

Moon(Ahrim),Chin(Susie),Kim(Hee Kyung),Kwa... Pathology 0000-00-00

...PIK3CA in distal EBD carcinoma and evaluate the association with clinicopathological factors. Ninety cases of distal ext...

Detection of PIK3CA mutations, including a novel mutation of V344G in exon 4,...

Allison(Derek B),Lilo(Mohammed T),Geddes(S... Cancer Cytopathol 0000-00-00

...PIK3CA, AKT, BRAF, EGFR, ERBB2, KRAS, and NRAS genes and tests of rearrangements for ALK and ROS1 genes.,A PIK3CA mutati...

Oncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-d...

Mancini(Maria L),Lien(Evan C),Toker(Alex) Oncotarget 0000-00-00

...PIK3CA, PTEN, and AKT, which lead to excessive and constitutive activation of Akt and downstream signaling that results ...

RAS mutation is a prognostic biomarker in colorectal cancer patients with met...

Osumi(Hiroki),Shinozaki(Eiji),Suenaga(Mits... Int J Cancer 0000-00-00

...PIK3CA mutations were 38.6% (51/132), 3.6% (5/132), 5.1% (7/132), 5.1% (7/132), and 8.7% (12/132), respectively. With a ...

Ridaforolimus improves the anti-tumor activity of dual HER2 blockade in uteri...

Hernandez(Silvia F),Chisholm(Sarah),Borger... Gynecol Oncol 0000-00-00

...PIK3CA mutated model.,These pilot data suggest that PIK3CA gene mutation may be an effective biomarker for selecting tho...

The dynamics of gene expression changes in a mouse model of oral tumorigenesi...

Foy(Jean-Philippe),Tortereau(Antonin),Caul... Oncotarget 0000-00-00

...PIK3CA mutations. Early changes observed in the 4-NQO model were associated with a trend toward a shorter oral cancer-fr...

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