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Analysis of PI3K pathway components in human cancers.

Daragmeh(Jamila),Barriah(Waseim),Saad(Bash... Oncol Lett 0000-00-00

...PIK3CA, PRR5, PSTPIP2, PTEN, FOX1, RHEB, RPS6KB1, TSC1, TP53, BCL2, CCND1, WFIKKN2, CREBBP, caspase-9, PTK2, EGFR, FAS, ...

Glucoregulatory, endocrine and morphological effects of [P5K]hymenochirin-1B ...

Owolabi(Bosede O),Ojo(Opeolu O),Srinivasan... Naunyn Schmiedebergs Arch P... 0000-00-00

...Pik3ca, Akt1 and Pkd1) were significantly up-regulated in skeletal muscle from animals treated with [P5K]hym-1B. Express...

Mutation of genes of the PI3K/AKT pathway in breast cancer supports their pot...

Tserga(Aggeliki),Chatziandreou(Ilenia),Mic... Virchows Arch 0000-00-00

...PIK3CA and AKT2 genes. Mutations of PIK3CA were found in our cohort in 21 cases (28 %), 10 (13 %) in exon 9 and 11(15 %)...

The Conundrum of Genetic "Drivers" in Benign Conditions.

Kato(Shumei),Lippman(Scott M),Flaherty(Kei... J Natl Cancer Inst 0000-00-00

...PIK3CA,TP53,CDKN2A, andNF1/2, all of which are considered hallmark drivers of specific cancers, can also be identified i...

Epigenetic and genetic burden measures are associated with tumor characterist...

O'Sullivan(Dylan E),Johnson(Kevin C),Skinn... Epigenetics 0000-00-00

...PIK3CA, and CDH1. Together, our work presents a novel framework for characterizing the epigenetic burden and adds to the...

Genetic profile of GNAQ-mutated blue melanocytic neoplasms reveals mutations ...

Pérez-Alea(Mileidys),Vivancos(Ana),Caratú(... Oncotarget 0000-00-00

...PIK3CA, NF1, INPP5B and GSK3B). Our results not only help understand the genetic complexity of these blue melanocytic le...

Prognostic impact of mutation profiling in patients with stage II and III col...

Shen(Yinchen),Han(Xiaohong),Wang(Jianfei),... Sci Rep 0000-00-00

...PIK3CA (exon9) mutations appeared more common in worse differentiation tumors (P = 0.032). Moreover, PIK3CA (E545K) muta...

Whole-exome sequencing of duodenal adenocarcinoma identifies recurrent Wnt/β-...

Yuan(Wei),Zhang(Zhou),Dai(Binghua),Wei(Qin... Cancer 0000-00-00

...PIK3CA), and SMAD family member 4 (SMAD4). Pathway scan indicated that the Wnt signaling pathway, regulation of the acti...

PD-L1 is an independent prognostic predictor in gastric cancer of Western pat...

Böger(Christine),Behrens(Hans-Michael),Mat... Oncotarget 0000-00-00

...PIK3CA-mutated GCs. A high PD-L1/PD-1 expression was associated with a significantly better patient outcome, and PD-L1 t...

Detection of PIK3CA mutations, including a novel mutation of V344G in exon 4,...

Allison(Derek B),Lilo(Mohammed T),Geddes(S... Cancer Cytopathol 0000-00-00

...PIK3CA, AKT, BRAF, EGFR, ERBB2, KRAS, and NRAS genes and tests of rearrangements for ALK and ROS1 genes.,A PIK3CA mutati...

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