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BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergi...

Goulielmaki(Maria),Koustas(Evangelos),Moys... Oncotarget 0000-00-00

...PIK3CA oncogenic pathways on the autophagic cell properties and on main components of the autophagic machinery like p62 ...

Frequency and clinicopathologic profile of PIK3CA mutant GISTs: molecular gen...

Lasota(Jerzy),Felisiak-Golabek(Anna),Wasag... Mod Pathol 0000-00-00

...PIK3CA being a common mutational target. In this study, the mutational hotspot in the PIK3CA kinase domain encoded by ex...

Relationship between Tumor Biomarkers and Efficacy in EMILIA, a Phase III Stu...

Baselga(José),Lewis Phillips(Gail D),Verma... Clin Cancer Res 0000-00-00

HER2-positive breast cancer is heterogeneous. Some tumors express mutations, like activating PIK3CA mutations or reduced...

Mutation distributions and clinical correlations of PIK3CA gene mutations in ...

Dirican(Ebubekir),Akkiprik(Mustafa),Özer(A... Tumour Biol 0000-00-00

...PIK3CA) mutation which has been identified in numerous BCa subtypes. In this review, correlations between PIK3CA mutatio...

Fulvestrant plus palbociclib versus fulvestrant plus placebo for treatment of...

Cristofanilli(Massimo),Turner(Nicholas C),... Lancet Oncol 0000-00-00

...PIK3CA mutational status in circulating DNA at baseline. This study is registered with ClinicalTrials.gov, NCT01942135.,...

Breast Cancer Heterogeneity Examined by High-Sensitivity Quantification of PI...

Myers(Meagan B),Banda(Malathi),McKim(Karen... Neoplasia 0000-00-00

...PIK3CA mutation levels were positively correlated with age. However, the PIK3CA H1047R mutant fraction distributions for...

High co-expression of PD-L1 and HIF-1α correlates with tumour necrosis in pul...

Chang(Yih-Leong),Yang(Ching-Yao),Lin(Mong-... Eur J Cancer 0000-00-00

...PIK3CA), anaplastic lymphoma kinase (ALK), and ROS1 (ROS1 proto-oncogene receptor tyrosine kinase) genes were examined.,...

Pilot Study of a Next-Generation Sequencing-Based Targeted Anticancer Therapy...

Park(Hyung Soon),Lim(Sun Min),Kim(Sora),Ki... PLoS One 0000-00-00

...PIK3CA mutation in parotid carcinosarcoma (partial response) and tracheal squamous cell carcinoma (stable disease; 21% r...

Genetic changes of non-small cell lung cancer under neoadjuvant therapy.

Warth(Arne),Endris(Volker),Stenzinger(Albr... Oncotarget 0000-00-00

...PIK3CA. The type of radiochemotherapy but not the duration of therapy impacted on the frequency of mutational changes.,W...

TP53, PIK3CA, FBXW7 and KRAS Mutations in Esophageal Cancer Identified by Tar...

Zheng(Huili),Wang(Yan),Tang(Chuanning),Jon... Cancer Genomics Proteomics 0000-00-00

...PIK3CA, FBXW7 and KRAS.,These results demonstrate that targeted sequencing can reliably identify mutations in individual...

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