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Thakur(T),Khare(S),Irriniki(S),Laroiya(I),... Clin Transl Oncol 2026-07-00

...PIK3CA (24%), TP53 (32%), and ERBB2 (9%). PIK3CA variants His1047Arg and Glu542Lys exhibited significantly higher varian...

Yang(X),Wang(J),An(H),He(Y),Gan(Y),Chen(Q)... Chin Med J (Engl) 2026-04-20

...PIK3CA, MUC17 , and PTEN , while FAT3, RYR2 , and CSMD3 were more frequently mutated in the HER2-zero subgroup. Furtherm...

Ren(J),Ren(Y),Tian(A),Cui(Z),Wang(D),Yu(H)... Brain 2026-08-03

...PIK3CAH1047R enhanced cell cycle and DNA replication pathways. Notably, MAP3K3I441M and PIK3CAH1047R double mutations sy...

Gagnon(KA),Hui(VW),Ching(T),Stoddard(AE),K... ACS Synth Biol 2026-02-20

...PIK3CAH1047R mutation and the ErbB2 amplification, both of which activate the PI3K-Akt pathway but paradoxically drive d...

Chen(L),Ding(W),Xu(P),Li(H),Zheng(Y) Diagn Pathol 2026-01-20

...PIK3CA NM_006218:exon5 c.1031T > G p.V344G. Following surgery and radiotherapy, no clinical or radiological evidence of ...

Schimmel(K),Hallmark(T),DeBose-Scarlett(E)... JACC Case Rep 2026-03-04

...PIK3CA activating mutation, which in this case may have driven endothelial cell proliferation. This novel discovery shed...

Zhao(J),Shi(H),Lu(B) Virchows Arch 2026-01-21

...PIK3CA (3/9), and PTEN (2/9), and absence of i(12p), confirming their somatic origin. Multi-region sequencing revealed t...

Xu(H),Dhillon(J) Adv Anat Pathol 2026-03-01

...PIK3CA and HRAS. Recently, it has been proposed to further subclassify differentiated PeIN. Extramammary Paget disease (...

Howran(J),Andrews(K),Ogawa(K),Cook(D),Purz... J Neurosurg Case Lessons 2026-01-05

...PIK3CA, and PTEN variants identified in the original GB, with acquisition of a TP53 mutation. This case illustrates a ra...

Vaklavas(C),Oliveira(M),Armstrong(AC),More... ESMO Open 2026-02-00

...PIK3CA/AKT1/PTEN-altered ER-positive, HER2-negative advanced breast cancer. Here, we report data from Parts I and J of S...