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TP53 BRCA1 CRISPR single-cell cancer

Pavel(Ana B),Sonkin(Dmitriy),Reddy(Anupama... BMC Syst Biol 0000-00-00

...PIK3CA inhibitor), PLX4720 (BRAF inhibitor), AZD6244 (MEK inhibitor), Erlotinib (EGFR inhibitor), and Nutlin-3 (MDM2 inh...

King(M A),Ganley(I G),Flemington(V) Oncogene 0000-00-00

...PIK3CA, AKT1, TSC1/2) are common in bladder cancer, yet small-molecule inhibitors of these nodes (FGFR/PTENi) show only ...

Du(L),Chen(X),Cao(Y),Lu(L),Zhang(F),Bornst... Oncogene 0000-00-00

...PIK3CA genetically engineered mouse model (PIK3CA-GEMM) in which wild-type PIK3CA is overexpressed in head and neck epit...

Yamaguchi(Kosuke),Iglesias-Bartolomé(Ramir... Oncotarget 0000-00-00

...PIK3CA+ cells in vitro and tumor xenografts. Moreover, ectopic expression of PIK3CA mutations into PIK3CA- HNSCC cells s...

Hudson(Kevin),Hancox(Urs J),Trigwell(Cath)... Mol Cancer Ther 0000-00-00

The PIK3CA gene, encoding the p110α catalytic unit of PI3Kα, is one of the most frequently mutated oncogenes in human ca...

Hwang(David H),Sholl(Lynette M),Rojas-Rudi... J Thorac Oncol 0000-00-00

...PIK3CA), erb-b2 receptor tyrosine kinase 2 (ERBB2), and anaplastic lymphoma receptor tyrosine kinase (ALK) and recurrent...

Wu(Shuhua),Wen(Feifei),Li(Yangyang),Gao(Xi... Tumour Biol 0000-00-00

...PIK3CA and PIK3CB that reverse multidrug resistance (MDR) can serve as predictive and prognostic markers as well as ther...

Ruzzenente(Andrea),Fassan(Matteo),Conci(Si... Ann Surg Oncol 0000-00-00

...PIK3CA (16.7 %); and in ICC were IDH1 (17.1 %), NRAS (17.1 %), and BAP1 (14.3 %). The presence of mutations in ALK, IDH1...

Harms(Paul W),Collie(Angela M B),Hovelson(... Mod Pathol 0000-00-00

...PIK3CA (3/15, 20%), AKT1 (1/15, 7%) and EZH2 (1/15, 7%). In conclusion, CK20-negative Merkel cell carcinoma display over...

van de Nes(Johannes),Gessi(Marco),Sucker(A... J Neurooncol 0000-00-00

...PIK3CA, ARID1A). Metastasized uveal melanomas exhibited mutations in GNAQ, GNA11 and BAP1. In contrast, MT-CNS almost ex...

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