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The mechanism of acquired resistance to irreversible EGFR tyrosine kinase inh...

Wu(Shang-Gin),Liu(Yi-Nan),Tsai(Meng-Feng),... Oncotarget 0000-00-00

...PIK3CA, BRAF, HER2, KRAS, NRAS, MEK1, AKT2, LKB1 and JAK2.,Afatinib-prescription record of our department of pharmacy fr...

Characterizing Molecular Variants and Clinical Utilization of Next-generation...

Gurda(Grzegorz T),Ambros(Tadeu),Nikiforova... Appl Immunohistochem Mol Mo... 0000-00-00

...PIK3CA (n=20), and FGFR1 (n=3). VaF comprised 46 single nucleotide variants (79%), 7 amplifications (12%), 3 frameshifts...

Genomics of gallbladder cancer: the case for biomarker-driven clinical trial ...

Sicklick(Jason K),Fanta(Paul T),Shimabukur... Cancer Metastasis Rev 0000-00-00

...PIK3CA, PBRM1, and TP53. Given the widespread use of tumor genomic profiling and the fact that most of the aforementione...

Genomic characterization of esophageal squamous cell carcinoma: Insights from...

Sasaki(Yasushi),Tamura(Miyuki),Koyama(Ryot... World J Gastroenterol 0000-00-00

...PIK3CA, KMT2D and NFE2L2, which had been previously implicated in ESCC. Several new recurrent alterations have also been...

Retrospective study testing next generation sequencing of selected cancer-ass...

Lo Iacono(Marco),Buttigliero(Consuelo),Mon... Oncotarget 0000-00-00

...PIK3CA p.I391M (19%), MET p.V378I (10%) and FGFR3 p.F384L/p.F386L (8%). TP53 p.P72R, MET p.V378I and CSFR1 SNPs were sig...

Copy number gain of PIK3CA and MET is associated with poor prognosis in head ...

Brauswetter(Diána),Dános(Kornél),Gurbi(Bia... Virchows Arch 0000-00-00

...PIK3CA genes. MET and PIK3CA copy numbers were analyzed by fluorescence in situ hybridization in tumor samples of 152 pa...

(Partial) Loss of BAF250a (ARID1A) in rectovaginal deep-infiltrating endometr...

Borrelli(G M),Abrão(M S),Taube(E T),Darb-E... Mol Hum Reprod 0000-00-00

...PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha) mutation. We might then be able to ident...

Sensitive methods for screening of the MEK1 gene mutations in patients with c...

Nicoś(M),Krawczyk(P),Jarosz(B),Sawicki(M),... Clin Transl Oncol 0000-00-00

...PIK3CA, NRAS, HER2, AKT1 and PTEN genes.,Using HRM and ASP-qPCR methods we identified one (0.7 %; 1/145) MEK1 substituti...

Next-generation sequencing reveals somatic mutations that confer exceptional ...

Lim(Sun Min),Park(Hyung Soon),Kim(Sangwoo)... Oncotarget 0000-00-00

...PIK3CA and PIK3CG mutations. Recurrently mutated genes in chromatin remodeling genes (BAP1; n = 2, 12%) and receptor tyr...

Detection rate of actionable mutations in diverse cancers using a biopsy-free...

Schwaederle(Maria),Husain(Hatim),Fanta(Pau... Oncotarget 0000-00-00

...PIK3CA (7%), and NOTCH1 (5.8%). In contrast, of 222 healthy volunteers, only one had an aberration (TP53). Ninety patien...

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