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PI3K-p110α mediates resistance to HER2-targeted therapy in HER2+, PTEN-defici...

Wang(Q),Liu(P),Spangle(J M),Von(T),Roberts... Oncogene 0000-00-00

...PIK3CA mutation or PTEN loss, which frequently results in sensitivity to p110α or p110β inhibitors, respectively. To exa...

Prognostic Utility of Molecular Factors by Age at Diagnosis of Colorectal Can...

McCleary(Nadine J),Sato(Kaori),Nishihara(R... Clin Cancer Res 0000-00-00

...PIK3CA mutations, and nuclear CTNNB1 expression status-on colorectal cancer-specific survival (CSS) and overall survival...

Next-Generation Sequencing of Matched Primary and Metastatic Rectal Adenocarc...

Crumley(Suzanne M),Pepper(Kristi L),Phan(A... Arch Pathol Lab Med 0000-00-00

...PIK3CA, and SMAD4.,-The somatic mutations identified in our rectal adenocarcinoma cohort showed a strong correlation to ...

NDRG4 stratifies the prognostic value of body mass index in colorectal cancer...

Zheng(Jianyong),Li(Yunming),Zhu(Shaojun),L... Oncotarget 0000-00-00

...PIK3CA mutation. Results showed that NDRG4 mRNA expression was decreased in tumor specimens and significantly correlated...

APOBEC3B high expression status is associated with aggressive phenotype in Ja...

Tsuboi(Miki),Yamane(Arito),Horiguchi(Jun),... Breast Cancer 0000-00-00

...PIK3CA by direct sequencing, polymorphic A3B deletion allele and human papillomavirus (HPV) infection in tumors.,A3B mRN...

Increased Expression of Phosphatidylinositol 3-Kinase p110α and Gene Amplific...

Yip(Wai Kien),He(Pei Yuan),Abdullah(Maizat... Pathol Oncol Res 0000-00-00

...PIK3CA copy number (Spearman's rho =0.324, P = 0.02). PI3K p110α expression and PIK3CA copy number did not associate wit...

Identification of Top-ranked Proteins within a Directional Protein Interactio...

Li(Xiu-Qing),Xing(Tim),Du(Donglei) Curr Issues Mol Biol 0000-00-00

...PIK3CA are among PIK3CA the top-ranked proteins in directional rankings. Eight proteins (ACVR1, CDC42, RAC1, RAF1, RHOA,...

PIK3CA(H1047R)- and Her2-initiated mammary tumors escape PI3K dependency by c...

Cheng(H),Liu(P),Ohlson(C),Xu(E),Symonds(L)... Oncogene 0000-00-00

...PIK3CA mutations, and are often associated with a worse prognosis. However, the role of PIK3CA mutations in the initiati...

Relationship between phosphoinositide-3-kinase genetic polymorphism and schiz...

Kordi-Tamandani(Dor Mohammad),Mir(Atefeh) Nord J Psychiatry 0000-00-00

...PIK3CA gene encodes the alpha catalytic subunit of the PI3K enzyme. The present study analysed the role of three SNPs of...

A Phase I Trial of BKM120 (Buparlisib) in Combination with Fulvestrant in Pos...

Ma(Cynthia X),Luo(Jingqin),Naughton(Michae... Clin Cancer Res 0000-00-00

...PIK3CA mutation or treatment cohort; however, loss of PTEN, progesterone receptor (PgR) expression, or mutation in TP53 ...

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