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TP53 BRCA1 CRISPR single-cell cancer

Harms(Paul W),Collie(Angela M B),Hovelson(... Mod Pathol 0000-00-00

...PIK3CA (3/15, 20%), AKT1 (1/15, 7%) and EZH2 (1/15, 7%). In conclusion, CK20-negative Merkel cell carcinoma display over...

van de Nes(Johannes),Gessi(Marco),Sucker(A... J Neurooncol 0000-00-00

...PIK3CA, ARID1A). Metastasized uveal melanomas exhibited mutations in GNAQ, GNA11 and BAP1. In contrast, MT-CNS almost ex...

Goh(Gerald),Walradt(Trent),Markarov(Vladim... Oncotarget 0000-00-00

...PIK3CA, PTEN, and TSC1) and to inactivate the Notch pathway (Notch1 and Notch2). TP53 mutations appear to be clinically ...

Yang(Wei),Hosford(Sarah R),Dillon(Lloye M)... Clin Cancer Res 0000-00-00

...PIK3CA-mutant xenografts were treated with the antiestrogen fulvestrant, the PI3K inhibitor GDC-0941 (pictilisib; varied...

Paleari(L),Puntoni(M),Clavarezza(M),DeCens... Clin Oncol (R Coll Radiol) 0000-00-00

...PIK3CA status. Hazard ratios for overall survival were meta-analysed according to PIK3CA status by inverse variance weig...

Fang(Wen-Liang),Huang(Kuo-Hung),Lan(Yuan-T... Oncotarget 0000-00-00

Mutations in genes involved in the PI3K/AKT pathway and amplifications of the PIK3CA gene in gastric cancer and their as...

Luk(Peter P),Weston(Jared D),Yu(Bing),Seli... Head Neck 0000-00-00

...PIK3CA, and NRAS mutations (22%; cumulative). The 5-year disease-free survival was 36%.,Salivary duct carcinoma demonstr...

Olasz(Judit),Doleschall(Zoltán),Dunai(Zsuz... Magy Onkol 0000-00-00

...PIK3CA) mutations and loss of phosphatase and tensin homolog (PTEN). The hiperactivated PI3K/AKT signaling can be associ...

Eberle(Carey A),Piscuoglio(Salvatore),Rakh... Histopathology 0000-00-00

...PIK3CA hotspot mutations, while the remaining case displayed a PIK3R1 somatic mutation.,Somatic mutations affecting PI3K...

Song(Bin),Cui(Heyang),Li(Yaoping),Cheng(Ca... Oncotarget 0000-00-00

...PIK3CA had better responses to chemotherapy and longer survival times than patients without PIK3CA mutations.,In a genet...

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