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, , and mutations in meningiomas.

Bujko(Mateusz),Kober(Paulina),Tysarowski(A... Oncol Lett 0000-00-00

...PIK3CA). Therefore, the aim of the present study was to assess the occurrence and potential use of these markers in pati...

Assessing the subcellular distribution of oncogenic phosphoinositide 3-kinase...

Layton(Meredith J),Rynkiewicz(Natalie),Ive... Biosci Rep 0000-00-00

...PIK3CA lead to an increase in instrinsic phosphoinositide kinase activity, but it is thought that increased access of PI...

BRCA1 protein levels and PIK3CA mutations as predictive biomarkers for respon...

Hilton(J),Weberpals(J),Lorimer(I),Amin(S),... Oncol Lett 0000-00-00

...PIK3CA mutation status was assessed by nested PCR amplification and DNA sequencing. BRCA1 protein levels and the PIK3CA ...

The genomics and genetics of endometrial cancer.

O'Hara(Andrea J),Bell(Daphne W) Adv Genomics Genet 0000-00-00

...PIK3CA, PIK3R1, PTEN, KRAS, FGFR2, ARID1A (BAF250a), and CTNNB1 (β-catenin), as well as epigenetic silencing of MLH1 res...

Possibility of molecular targeting therapy for the treatment of cancer of unk...

Ohta(Shoichiro),Cho(Yukiko),Shibata(Masaha... Exp Ther Med 0000-00-00

...PIK3CA and BRAF gene mutations and clinical features for possibilities for new therapies in patients with CUP. Nine pati...

PIK3CA mutation and methylation influences the outcome of colorectal cancer.

Iida(Satoru),Kato(Shunsuke),Ishiguro(Megum... Oncol Lett 0000-00-00

...PIK3CA and 0 or 1 methylated genes (P=0.0059). Additionally, multivariate analysis revealed that the PIK3CA mutation and...

Acquired/intratumoral mutation of KRAS during metastatic progression of color...

Otsuka(Kazunori),Satoyoshi(Rika),Nanjo(Hir... Oncol Lett 0000-00-00

...PIK3CA, and immunohistochemistry for glutathione S-transferase II (GSTP) and EGFR. In the current study, we identified a...

Mutation and expression of multiple treatment response-related genes in a pop...

Lu(Hong-Yang),Su(Dan),Pan(Xiao-Dan),Jiang(... Oncol Lett 0000-00-00

...PIK3CA) genes, and mRNA levels of EGFR, ERCC1, class III β-tubulin (TUBB3) and TYMS, separately, in paraffin tissue bloc...

Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Me...

Davies(Michael A),Stemke-Hale(Katherine),L... Clin Cancer Res 0000-00-00

...PIK3CA, and KIT were detected by mass spectroscopy genotyping. Phosphorylated AKT (Ser473 and Thr308), P-GSK3alpha/beta,...

PIK3CA Mutations are Common in Many Tumor Types and are Often Associated With...

Stachler(Matthew D),Rinehart(Elizabeth M),... Appl Immunohistochem Mol Mo... 0000-00-00

...PIK3CA mutations since much interest has been placed on PIK3CA targeted therapy.,We performed multiplexed tumor genotypi...

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