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Amplicon mapping and transcriptional analysis pinpoint cyclin L as a candidat...

Redon(Richard),Hussenet(Thomas),Bour(Gaéta... Cancer Res 2002-12-10

...PIK3CA, p63, and eIF-5A2. However, none of these genes was found included in a narrow high-level amplification. Recently...

p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas.

Singh(Bhuvanesh),Reddy(Pabbathi G),Goberdh... Genes Dev 2002-05-13

...PIK3CA, encoding the p110alpha catalytic subunit of PI3K, is identified as an oncogene involved in upper aerodigestive t...

Genetic alterations in cervical carcinomas: frequent low-level amplifications...

Zhang(Anju),Månér(Susanne),Betz(Regina),An... Int J Cancer 2002-10-10

...PIK3CA at 3q26.3, TERT at 5p15.33, C-MYC at 8q24, CCND1 at 11q13.3, ERBB2 at 17q21.2 and locus region 20q13.2. Amplifica...

Genome wide detection of oncogene amplifications in nasopharyngeal carcinoma ...

Hui(Angela Bik-Yu),Lo(Kwok-Wai),Teo(Peter ... Int J Oncol 2002-05-31

...PIK3CA at 3q26.3. Other high level amplified oncogenes included NRAS, RAF1, MYB, EGFR, FGF4, EMS1, and D17S167. Highest ...

Genomic copy number analysis of non-small cell lung cancer using array compar...

Massion(Pierre P),Kuo(Wen-Lin),Stokoe(Davi... Cancer Res 2002-08-08

...PIK3CA, the alpha catalytic subunit of phosphatidylinositol 3-kinase (PI3K), is in this region. The PIK3CA copy number i...

Detection of multiple gene amplifications in glioblastoma multiforme using ar...

Hui(A B),Lo(K W),Yin(X L),Poon(W S),Ng(H K... Lab Invest 2001-06-07

...PIK3CA (64.3%), EGFR (57.1%), CSE1L (57.1%), NRAS (50%), MYCN (42.9%), FGR (35.7%), ESR (35.7%), PGY1 (35.7%), and D17S1...

A simple specific pattern of chromosomal aberrations at early stages of head ...

Redon(R),Muller(D),Caulee(K),Wanherdrick(K... Cancer Res 2001-06-14

...PIK3CA and p63, located respectively at 3q26 and at 3q28. Although PIK3CA or p63 were preferentially gained in few cases...

SNO is a probable target for gene amplification at 3q26 in squamous-cell carc...

Imoto(I),Pimkhaokham(A),Fukuda(Y),Yang(Z Q... Biochem Biophys Res Commun 2001-09-27

...PIK3CA. Amplification of SNO was accompanied by significant increases in its expression level, suggesting that this gene...

PIK3CA as an oncogene in cervical cancer.

Ma(Y Y),Wei(S J),Lin(Y C),Lung(J C),Chang(... Oncogene 2000-07-06

...PIK3CA, which is located in 3q26.3, in cervical tumorigenesis. PIK3CA is known to be involved in the PI 3-kinase/AKT sig...

Growth suppression of human ovarian cancer cells by adenovirus-mediated trans...

Minaguchi(T),Mori(T),Kanamori(Y),Matsushim... Cancer Res 2000-01-24

...PIK3CA) is frequently activated in ovarian cancers; therefore, overexpression of the PTEN product through gene transfer ...

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