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TP53 BRCA1 CRISPR single-cell cancer

Tong(Carol Y K),Hui(Angela B Y),Yin(Xiao-L... J Neurosurg 2004-02-17

...PIK3CA (46.2%), PGY1 (38.5%), MET (38.5%), ERBB2 (38.5%), and CSE1L (38.5%). The gain in gene copy numbers was confirmed...

Broderick(Daniel K),Di(Chunhui),Parrett(Ti... Cancer Res 2004-09-09

...PIK3CA as an oncogene in a wider spectrum of adult and pediatric brain tumors and suggest that PIK3CA may be a useful di...

Woenckhaus(Joachim),Steger(Klaus),Werner(E... J Pathol 2003-01-07

PIK3CA, encoding the catalytic subunit p110alpha of phosphatidylinositol 3-kinase (PI3K), is activated in malignant dise...

Mao(Xin),Orchard(Guy),Lillington(Debra M),... Blood 2003-03-13

...PIK3CA (3q26), HRAS (11p15), MYBL2 (20q13), and ZNF217 (20q13) in 3 cases (43%). Amplification of JUNB was studied in 10...

Byun(Do-Sun),Cho(Kyucheol),Ryu(Byung-Kyu),... Int J Cancer 2003-03-31

...PIK3CA are mutually exclusive events in gastric tumorigenesis. Amplification of PIK3CA was strongly associated with incr...

Imoto(Issei),Yuki(Yasuhiro),Sonoda(Itaru),... Cancer Res 2003-12-04

...PIK3CA in our panel of ESC cell lines and primary tumors. In patients with ESC, a higher mRNA expression level of ZASC1 ...

Schraml(Peter),Schwerdtfeger(Georg),Burkha... Am J Pathol 2003-09-22

...PIK3CA on 3q (66%), PAK1 on 11q (59%), KRAS2 on 12p (55%), and STK15 on 20q (55%). The 11q13-q14 amplicon, represented b...

Zhang(Lin),Yang(Nuo),Katsaros(Dionyssios),... Cancer Res 2003-08-13

The gene of phosphatidylinositol 3-kinase catalytic subunit alpha (PIK3CA) has been implicated as an oncogene in ovarian...

Worsham(Maria J),Pals(Gerard),Schouten(Jan... Arch Otolaryngol Head Neck ... 2003-08-18

...PIK3CA (encodes a PI3 kinase) located at 3q26.3.,We provide evidence for the role of 3 critical pathways in the developm...

Snijders(Antoine M),Nowee(Marlies E),Fridl... Oncogene 2003-08-01

...PIK3CA and KRAS, previously suggested to be candidate driver genes for amplification, mapped outside copy number maxima ...

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