...PIK3CA, and MYC), tumor suppressor genes (TP53, CDH1, and ARID1A), and regulators of genome stability and cell architect...
...PIK3CA, AKT1/PTEN, ESR1, plus PD-L1 testing in mTNBC); for HR+/HER2- mBC, first-line endocrine therapy plus CDK4/6 inhib...
...PIK3CA mutations and had significantly fewer TERT promoter and PTEN mutations, compared with the mutation-negative group...
...PIK3CA mutations and YAP1 amplification are prevalent cervical cancer drivers. STK11 mutations and deletions co-occur si...
PIK3CA-Related Overgrowth Spectrum (PROS) is a highly heterogeneous disease. Facial Infiltrating Lipomatosis (FIL) is a ...
...PIK3CA are key targets strongly associated with depression, which is consistent with the molecular docking results. Fina...
...PIK3CA mutations. No primary ovarian, endometrial, or renal tumor was detected, supporting a diagnosis of primary perito...
...PIK3CA mutations were significantly more frequent in the Non-Germline and non-gBRCA groups than in the Germline and gBRC...
...PIK3CA, MTOR, AKT2, AKT3), while machine learning validated AKT2 as a critical node. ASNS was consistently upregulated 4...
...PIK3CA for tumor growth both in vitro and in vivo. We first generated a "KPA" cell line by genetically deleting Pik3ca f...
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