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TP53 BRCA1 CRISPR single-cell cancer

Samuels(Yardena),Diaz(Luis A),Schmidt-Kitt... Cancer Cell 2005-09-06

...PIK3CA selectively regulated the phosphorylation of AKT and the forkhead transcription factors FKHR and FKHRL1. PIK3CA m...

Hartmann(Christian),Bartels(Gesine),Gehlha... Acta Neuropathol 2005-10-04

...PIK3CA mutations and 10 (14%) PTEN mutations were found. All mutations in PIK3CA located to exons 1, 9 and 20, thereby s...

Campbell(Ian G),Russell(Sarah E),Choong(Da... Cancer Res 2004-11-30

...PIK3CA has been reported among a large series of colorectal cancers. However, the relevance of PIK3CA mutation in other ...

Weir(Barbara),Zhao(Xiaojun),Meyerson(Matthew) Cancer Cell 2004-12-14

...PIK3CA, and EGFR genes, among others. With further development of targeted cancer therapies and improvement in genome an...

Massion(Pierre P),Taflan(Peter M),Shyr(Yu)... Am J Respir Crit Care Med 2004-12-14

...PIK3CA) and phosphorylated Akt expression in invasive and preinvasive lung cancers. We sought to determine at what stage...

Knobbe(Christiane B),Reifenberger(Guido) Brain Pathol 2004-01-12

...PIK3CA, PIK3CD, and PIK3C2B) revealed amplification of PIK3C2B (1q32) in 6 tumors (6%). Overexpression of PIK3C2B mRNA w...

Yokoi(Sana),Yasui(Kohichiroh),Iizasa(Toshi... Clin Cancer Res 2004-06-10

...PIK3CA) in those cell lines and also in 25 primary NSCLC tumors. Because the TERC gene encodes the RNA component of huma...

Miller(Charles T),Moy(Justin R),Lin(Lin),S... Clin Cancer Res 2004-06-10

...PIK3CA in 5 of 87 (5.7%), C-MYC in 4 of 87 (4.6%), DYRK2 in 2 of 87 (2.3%), and AIB1, AKT1, and IGF1R were amplified in ...

Estilo(Cherry L),O-Charoenrat(Pornchai),Ng... Clin Cancer Res 2004-01-06

...PIK3CA in the pathogenesis of oral tongue SCC.,The association between gene copy number for SCCRO and PIK3CA measured by...

Yen(Chueh-Chuan),Chen(Yann-Jang),Lu(Kai-Hs... Int J Oncol 2004-07-09

...PIK3CA and TP63 in 100% and 80% of the cases. Average copy number of PIK3CA per haploid genome was greater than that of ...

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