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TP53 BRCA1 CRISPR single-cell cancer

Samuels(Yardena),Diaz(Luis A),Schmidt-Kitt... Cancer Cell 2005-09-06

...PIK3CA selectively regulated the phosphorylation of AKT and the forkhead transcription factors FKHR and FKHRL1. PIK3CA m...

Janmaat(Maarten L),Rodriguez(José A),Galle... Int J Cancer 2005-12-13

...pik3ca, and k-ras, and basal protein expression levels of PTEN. The egfr mutant NSCLC cell line H1650 as well as the egf...

Hartmann(Christian),Bartels(Gesine),Gehlha... Acta Neuropathol 2005-10-04

...PIK3CA mutations and 10 (14%) PTEN mutations were found. All mutations in PIK3CA located to exons 1, 9 and 20, thereby s...

Wu(Guojun),Mambo(Elizabeth),Guo(Zhongmin),... J Clin Endocrinol Metab 2005-09-14

...PIK3CA gene.,We found no PIK3CA gene mutations in 37 benign thyroid adenomas, 52 papillary thyroid cancers, 25 follicula...

Moroni(Mauro),Veronese(Silvio),Benvenuti(S... Lancet Oncol 2005-05-24

...PIK3CA.,Eight of nine of patients with objective responses who were assessable by fluorescence in-situ hybridisation (FI...

Wang(Yun),Kristensen(Gunnar B),Helland(Asl... Am J Clin Pathol 2005-10-14

...PIK3CA]; phosphatase and tensin homologue [PTEN]; phosphorylated AKT [p-AKT]; and phosphorylated extracellular signal-re...

Morrow(Christopher J),Gray(Alexander),Dive... FEBS Lett 2005-10-19

Recent studies have identified conserved missense mutations in PIK3CA, the gene encoding the catalytic phosphatidylinosi...

Knobbe(C B),Trampe-Kieslich(A),Reifenberge... Neuropathol Appl Neurobiol 2005-10-27

...PIK3CA (3q26.3) and phosphatidylinositol-3-kinase enhancer (PIKE) (CENTG1, 12q14), for genetic alteration and aberrant e...

Bachman(Kurtis E),Argani(Pedram),Samuels(Y... Cancer Biol Ther 2005-03-29

...PIK3CA, with the majority of mutations located in the kinase domain. These results demonstrate that PIK3CA is the most m...

Or(Yan-Yan),Hui(Angela Bik-Yu),Tam(Ka-Ying... Int J Oncol 2005-05-02

...PIK3CA, a candidate oncogene located at 3q26.32 adjacent to this 3q amplicon was investigated by real-time quantitative ...

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