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Mutation analysis of PIK3CA and PIK3CB in esophageal cancer and Barrett's eso...

Phillips(Wayne A),Russell(Sarah E),Ciavare... Int J Cancer 2006-05-22

...PIK3CA in 101 samples from 95 individuals with esophageal cancer and/or Barrett's esophagus. Somatic mutation of PIK3CA ...

Molecular analysis of the PI3K-AKT pathway in uterine cervical neoplasia: fre...

Bertelsen(Bjørn I),Steine(Solrun J),Sandve... Int J Cancer 2006-04-18

...PIK3CA amplification using quantitative real-time polymerase chain reaction. PIK3CA gene copy number was estimated to be...

Mutation of the PIK3CA gene in anaplastic thyroid cancer.

García-Rostán(Ginesa),Costa(Angela M),Pere... Cancer Res 2006-01-18

...PIK3CA, are common (25-40%) among colorectal, gastric, breast, ovarian cancers, and high-grade brain tumors. Moreover, P...

ERBB2 kinase domain mutation in the lung squamous cell carcinoma.

Lee(Jong Woo),Soung(Young Hwa),Kim(Su Youn... Cancer Lett 2006-07-26

...PIK3CA and BRAF genes in the squamous cell carcinoma with the ERBB2 mutation, and found that the tumor did not harbor an...

Phosphoinositide 3-kinases as drug targets in cancer.

Stephens(Len),Williams(Roger),Hawkins(Phil... Curr Opin Pharmacol 2006-05-24

...PIK3CA) are present in a variety of cancers. We now know that three of the most frequent mutations in cancer constitutiv...

Somatic mutation and gain of copy number of PIK3CA in human breast cancer.

Wu(Guojun),Xing(Mingzhao),Mambo(Elizabeth)... Breast Cancer Res 2006-02-23

...PIK3CA inhibitor LY294002 and compared the apoptosis status in cells with and without PIK3CA mutation.,We identified a 2...

PIK3CA mutations are an early genetic alteration associated with FGFR3 mutati...

López-Knowles(Elena),Hernández(Silvia),Mal... Cancer Res 2006-09-28

...PIK3CA mutations were strongly associated with FGFR3 mutations: 18 of 69 (26%) FGFR3(mut) tumors were PIK3CA(mut), versu...

PIK3CA gene mutations in endometrial carcinoma: correlation with PTEN and K-R...

Velasco(Ana),Bussaglia(Elena),Pallares(Jud... Hum Pathol 2006-12-14

...PIK3CA gene, which encode the p110alpha catalytic subunit of PI3K. PIK3CA mutations cluster to the helical (exon 9) and ...

Epidermal growth factor receptor mutation in lung cancer are linked to bronch...

Blons(Hélène),Côté(Jean-François),Le Corre... Am J Surg Pathol 2006-10-26

...PIK3CA for mutations in 2 groups of White patients with nonsmall cell lung cancer (45 cancers from women and 46 cancers ...

ERBB2 kinase domain mutation in a gastric cancer metastasis.

Lee(Jong Woo),Soung(Young Hwa),Kim(Su Youn... APMIS 2006-02-08

...PIK3CA and BRAF genes in the sample with the ERBB2 mutation, and found that this metastatic carcinoma did not harbor any...

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