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Mutations of PIK3CA are rare in cutaneous melanoma.

Omholt(Katarina),Kröckel(Doris),Ringborg(U... Melanoma Res 2006-07-14

...PIK3CA is altered in cutaneous melanoma, we screened a series of 101 melanoma metastases. We identified PIK3CA missense ...

Array-comparative genomic hybridization to detect genomewide changes in micro...

Liu(Chung-Ji),Lin(Shu-Chun),Chen(Yann-Jang... Mol Carcinog 2006-10-13

...PIK3CA, MYB, MDR1, HRAS, GARP, CCND2, FES, HER2, SIS, and SRY. The highest frequencies of losses were detected in p44S10...

PIK3CA and TFRC located in 3q are new prognostic factors in esophageal squamo...

Wada(Shinsuke),Noguchi(Tsuyoshi),Takeno(Sh... Ann Surg Oncol 2006-11-07

...PIK3CA, and TFRC.,Expression of beta-actin mRNA was detected in 67 (55.8%) of 120 samples, with PIK3CA mRNA expression i...

Somatic mutations of ERBB2 kinase domain in gastric, colorectal, and breast c...

Lee(Jong Woo),Soung(Young Hwa),Seo(Si Hyun... Clin Cancer Res 2006-02-09

...PIK3CA, and BRAF genes in the 16 samples with ERBB2 mutations, and found that all of the 3 colorectal carcinoma samples ...

Clinical significance of immunocytochemistry for PIK3CA as a carcinogenesis-r...

Goto(Tomoko),Takano(Masashi),Sasa(Hidenori... Oncol Rep 2006-06-01

...PIK3CA provided the best method for distinguishing CIN3. Thus, expression of PIK3CA was observed in liquid-based cytolog...

Mutation analysis of PIK3CA and PIK3CB in esophageal cancer and Barrett's eso...

Phillips(Wayne A),Russell(Sarah E),Ciavare... Int J Cancer 2006-05-22

...PIK3CA in 101 samples from 95 individuals with esophageal cancer and/or Barrett's esophagus. Somatic mutation of PIK3CA ...

Human tumor mutants in the p110alpha subunit of PI3K.

Liu(Zhenning),Roberts(Thomas M) Cell Cycle 2006-08-07

The PI3K-Akt pathway is frequently upregulated in human tumors. Recently, somatic mutations of PIK3CA, encoding p110alph...

Sequence mutations and amplification of PIK3CA and AKT2 genes in purified ova...

Nakayama(Kentaro),Nakayama(Naomi),Kurman(R... Cancer Biol Ther 2006-12-11

...PIK3CA. Unlike mutations in ERBB2, KRAS and BRAF which are mutually exclusive in SBTs, coamplification of PIK3CA and AKT...

PI 3-kinases: hidden potentials revealed.

Vogt(Peter K),Bader(Andreas G),Kang(Sohye) Cell Cycle 2006-06-05

...PIK3CA, the gene coding for the catalytic subunit p110alpha of PI 3-kinase, are oncogenic in the animal. These mutations...

PIK3CA mutations in intraductal papillary mucinous neoplasm/carcinoma of the ...

Schönleben(Frank),Qiu(Wanglong),Ciau(Nancy... Clin Cancer Res 2006-09-11

...PIK3CA and activate the Akt signaling pathway. The mutational status of PIK3CA in intraductal papillary mucinous neoplas...

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