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[Malignant melanoma with anaplastic lymphoma kinase positivity: a clinicopath...

Chen(Z),Yang(HJ),Cao(H),Xu(LM),Teng(XD) Zhonghua Bing Li Xue Za Zhi 2026-01-08

...PIK3CA were detected in any of the cases. Conclusions: Both ALK fusion and ATI-driven ALK expression patterns can presen...

Age- and sex-based differences in the genomic profiles of patients with gastr...

Li(S),Liu(L),Gandhi(N),Farrell(A),Lou(E),S... Oncologist 2026-02-05

...PIK3CA mutations and dMMR/MSI-H were increased in females. Our study queries one of the largest datasets of GI- and P-NE...

Cost-effectiveness of inavolisib plus palbociclib-fulvestrant versus palbocic...

Zhu(J),Ding(Y),Li(Z),Liu(W) Breast 2026-02-00

...PIK3CA mutations from both United States (U.S.) and Chinese healthcare system perspectives. A partitioned survival model...

Predictive Value of PIK3CA Mutations for Response to CDK4/6 Inhibitors in Hor...

Qureshi(Z),Jamil(A),Wali(N),Okobi(TJ),Kahl... Am J Clin Oncol 2026-01-06

...PIK3CA than in patients with PIK3CA alteration (53/180 (29%) versus 13/85 (15%). PIK3CA mutation correlates with poor PF...

A droplet digital LAMP-based lab-on-a-disc system for multiplex allele-specif...

Lu(H),Wang(Q),Tang(X),Jiang(Y),Shen(J),Yan... Biosens Bioelectron 2026-04-01

...PIK3CA mutation frequency in adjacent tissue effectively predicts breast cancer prognosis, while serum PIK3CA profiles c...

A Clinically Derived TCM Decoction (WD-3) Attenuates Malignant Phenotypes of ...

Zhu(H),Zhao(W),Qian(J),Zhu(X),Zhang(C),Gen... Biol Proced Online 2026-01-07

...PIK3CA, PPARG). Pathway enrichment and docking converged on the PPARγ (PPARG)/AMPK axis. Experimentally, WD-3 suppressed...

Bile duct tumor thrombus (intraductal polypoid growth)-positive intrahepatic ...

Mitsui(A),Esaki(M),Nara(S),Arai(Y),Nakamur... J Pathol 2026-05-00

...PIK3CA, MUC17, MAP3K4, MUC2, BRAF, NF1). Genetic landscapes were similar in SDT iCCA with and without BDTT; recurrent mu...

Prognostic and monitoring value of circulating tumor DNA at multiple clinical...

Park(MS),Youn(Y),Kim(JA),Cho(EH),Do(IG),Wo... Breast Cancer 2026-03-00

...PIK3CA mutations were the second most common, detected in 11.6%, 4.5%, and 5.8% of patients, respectively. ctDNA positiv...

Sequential use of PI3K/AKT/mTOR pathway inhibitors alpelisib and everolimus i...

Shen(S),Teysir(J),Safonov(A),Bromberg(M),C... Breast Cancer Res 2026-01-31

...PIK3CA-mutant HR+/HER2- MBC. The efficacy and safety of sequential treatment with these pathway inhibitors is not well d...

Insulin signaling pathway related m6A methylated biomarker for type 2 diabete...

Dong(J),Zhang(Y),Li(YL),Wu(LJ),Wang(S),Che... Nutr Metab (Lond) 2026-01-31

...PIK3CA/AKT1. The mechanism of FTO on m6A modification of PIK3CA was validated by methylated RNA immunoprecipitation (MeR...

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