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TP53 BRCA1 CRISPR single-cell cancer

Gymnopoulos(Marco),Elsliger(Marc-André),Vo... Proc Natl Acad Sci U S A 2007-05-14

...PIK3CA, the gene coding for the catalytic subunit p110alpha of phosphatidylinositol 3-kinase (PI3K), were examined for t...

Yarbrough(Wendell G),Whigham(Amy),Brown(Br... Int J Radiat Oncol Biol Phy... 2007-11-28

...PIK3CA was overexpressed in HPV(+)-associated HNSCC compared with the expression in HPV(-) HNSCC. Activation of PIK3CA b...

Freier(Kolja),Schwaenen(Carsten),Sticht(Ca... Oral Oncol 2007-11-20

...PIK3CA, whereas deletions affected TRAILR1 and ATM. Furthermore, a distinct high-level amplification of the fibroblast g...

Müller(Claudia I),Miller(Carl W),Hofmann(W... Leuk Res 2007-01-30

Lipid kinase PIK3CA mutations have been described in several cancers. They clustered in two 'hot spots' located in helic...

Nosho(Katsuhiko),Yamamoto(Hiroyuki),Takaha... Carcinogenesis 2007-08-07

...PIK3CA mutation. Multiple logistic analysis showed that lymphatic invasion and RASSF2 methylation with KRAS, BRAF or PIK...

Gallia(Gary L),Rand(Vikki),Siu(I-Mei),Eber... Mol Cancer Res 2007-02-12

...PIK3CA in 73 glioblastoma samples by PCR amplification followed by direct DNA sequencing. Overall, PIK3CA mutations were...

Mikami(Masashi),Nosho(Katsuhiko),Yamamoto(... Eur J Cancer 2007-02-09

...PIK3CA in 310 early colorectal tumours. beta-catenin mutation was detected in 7.1% of 310 tumours. beta-catenin mutation...

Boyault(Sandrine),Rickman(David S),de Reyn... Hepatology 2007-01-23

...PIK3CA and TP53. In these first groups, we detected specific activation of the AKT pathway. G3 tumors were typified by m...

Maruyama(Naomi),Miyoshi(Yasuo),Taguchi(Tet... Clin Cancer Res 2007-04-24

...PIK3CA mutations and p53 mutation status. PIK3CA mutations were significantly (P < 0.05) associated with a favorable pro...

Willner(Julia),Wurz(Kaitlyn),Allison(Kimbe... Hum Pathol 2007-05-01

...PIK3CA occurs by gene amplification in SC but via somatic mutation of PIK3CA or PTEN in EC and CC. PIK3CA mutations are ...

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