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PIK3CA cooperates with other phosphatidylinositol 3'-kinase pathway mutations...

Oda(Katsutoshi),Okada(Jennifer),Timmerman(... Cancer Res 2008-11-26

...PIK3CA. In breast, colon, and endometrial cancers in which the PI3K pathway is activated by a combination of mutant PIK3...

Class I PI3K in oncogenic cellular transformation.

Zhao(L),Vogt(P K) Oncogene 2008-10-08

...PIK3CA, the gene encoding p110 alpha, is mutated frequently in common cancers, including carcinoma of the breast, prosta...

Coordinated epidermal growth factor receptor pathway gene overexpression pred...

Jimeno(Antonio),Tan(Aik Choon),Coffa(Jordy... Cancer Res 2008-06-10

...PIK3CA mutations and gene amplification by fluorescence in situ hybridization and multiplex ligation-dependent probe amp...

Dysregulation of the phosphatidylinositol 3-kinase pathway in thyroid neoplasia.

Paes(John E),Ringel(Matthew D) Endocrinol Metab Clin North Am 2008-08-18

...PIK3CA). These genetic abnormalities have been particularly associated with follicular thyroid neoplasia and anaplastic ...

Highly prevalent genetic alterations in receptor tyrosine kinases and phospha...

Liu(Zhi),Hou(Peng),Ji(Meiju),Guan(Haixia),... J Clin Endocrinol Metab 2008-09-08

...PIK3Ca, PIK3Cb, and PDK1 genes in the PI3K/Akt pathway. Mutations of Ras, PIK3Ca, PTEN, and BRAF genes and RET/PTC rearr...

Somatic FGFR3 and PIK3CA mutations are present in familial seborrhoeic kerato...

Hafner(C),Vogt(T),Landthaler(M),Müsebeck(J... Br J Dermatol 2008-10-23

...PIK3CA mutations have been reported to be involved in the pathogenesis of sporadic SK, we analysed five SKs of an affect...

Defining the blueprint of the cancer genome.

Velculescu(Victor E) Carcinogenesis 2008-07-29

...PIK3CA gene encoding p110alpha phosphatidylinositol 3-kinase and in related pathway genes in >30% of colon and breast ca...

SnoN overexpression is predictive of poor survival in patients with esophagea...

Akagi(Ichiro),Miyashita(Masao),Makino(Hiro... Ann Surg Oncol 2008-12-04

...PIK3CA which encodes the p110alpha catalytic subunit of phosphatidylinositol (PI) 3-kinase, a telomerase RNA component (...

Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis.

Jia(Shidong),Liu(Zhenning),Zhang(Sen),Liu(... Nature 2008-09-18

...Pik3ca), impeded tumorigenesis with a concomitant diminution of Akt phosphorylation. Taken together, our findings demons...

Somatic oncogenic mutations, benign skin lesions and cancer progression: wher...

Toll(Agustí),Real(Francisco X) Cell Cycle 2008-10-22

Somatic oncogenic activating mutations in FGFR3 and/or PIK3CA have recently been described in benign epithelial cutaneou...

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