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TP53 BRCA1 CRISPR single-cell cancer

Kawano(Osamu),Sasaki(Hidefumi),Okuda(Katsu... Lung Cancer 2008-04-11

...PIK3CA amplification. PIK3CA amplification incidence was significantly higher in male, smoker and squamous cell carcinom...

Quaye(Lydia),Gayther(Simon A),Ramus(Susan ... Clin Cancer Res 2008-10-08

...PIK3CA, and survival after a diagnosis of epithelial ovarian cancer.,We evaluated the association between 34 tagging sin...

Hui(Rosaline C-Y),Gomes(Ana R),Constantini... Mol Cell Biol 2008-10-20

...PIK3CA. As was the case for FOXO3a, the expression or knockdown of p110alpha was sufficient to amplify or reduce PI3K/Ak...

Zunder(Eli R),Knight(Zachary A),Houseman(B... Cancer Cell 2008-08-28

...PIK3CA) is the most frequently mutated kinase in human cancer, and numerous drugs targeting this kinase are currently in...

Stemke-Hale(Katherine),Gonzalez-Angulo(Ana... Cancer Res 2008-09-08

...PIK3CA, AKT, and PTEN mutations and the effects of PIK3CA mutations on responsiveness to PI3K inhibition in vitro and on...

Ladu(Sara),Calvisi(Diego F),Conner(Elizabe... Gastroenterology 2008-11-14

...PIK3CA/Akt/mTOR and c-Myb/COX-2 pathways were similarly activated, with levels of PIK3CA/Akt, mTOR, and c-Myb being inve...

Lerma(Enrique),Catasus(Lluis),Gallardo(Alb... Virchows Arch 2008-11-24

...PIK3CA were identified among the 27 Her-2 positive BC, whereas only one exon 9 PIK3CA mutation was detected in a triple ...

Wee(Susan),Wiederschain(Dmitri),Maira(Sauv... Proc Natl Acad Sci U S A 2008-10-06

...PIK3CA. Tumors harboring activated p110alpha, the protein product of PIK3CA, require p110alpha activity for growth and s...

Yamamoto(Hiromasa),Shigematsu(Hisayuki),No... Cancer Res 2008-09-18

...PIK3CA inhibited colony formation of cell lines with PIK3CA mutations or gains but was not effective in PIK3CA wild-type...

Velho(Sérgia),Moutinho(Cátia),Cirnes(Luís)... BMC Cancer 2008-11-18

...PIK3CA mutations are frequently found in sporadic colorectal cancer (CRC). In contrast to KRAS and PIK3CA mutations, BRA...

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