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Oncogenic mutations of the PIK3CA gene in head and neck squamous cell carcino...

Murugan(Avaniyapuram Kannan),Hong(Nguyen T... Int J Oncol 2008-03-20

...PIK3CA mutations have not been examined. Status of PI3K signaling related genes (PTEN-RAS-EGFR) in the presence of PIK3C...

Integrated profiling of basal and luminal breast cancers.

Adélaïde(José),Finetti(Pascal),Bekhouche(I... Cancer Res 2008-01-15

...PIK3CA. Potential gene breaks involved ETV6 and FLT3. Second, we analyzed both aCGH and gene expression profiles for 42 ...

EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-, or TFG-ALK fus...

Shinmura(Kazuya),Kageyama(Shinji),Tao(Hong... Lung Cancer 2008-11-18

...PIK3CA genes in these two carcinomas, however, a Pro177Ser mutation of the p53 gene was detected in the carcinoma that c...

Targeting phosphoinositide 3-kinase: moving towards therapy.

Marone(Romina),Cmiljanovic(Vladimir),Giese... Biochim Biophys Acta 2008-03-27

...PIK3CA locus coding for PI3Kalpha, by loss of function of the lipid phosphatase and tensin homolog deleted in chromosome...

Clinicopathological analysis of papillary thyroid cancer with PIK3CA alterati...

Abubaker(Jehad),Jehan(Zeenath),Bavi(Prasha... J Clin Endocrinol Metab 2008-04-10

...PIK3CA, N2-RAS, and BRAF genes.,PIK3CA amplification was seen in 265 of 499 PTC cases analyzed (53.1%); PIK3CA gene muta...

Expression signatures in lung cancer reveal a profile for EGFR-mutant tumours...

Angulo(B),Suarez-Gauthier(A),Lopez-Rios(F)... J Pathol 2008-03-25

The development of targeted therapies creates a need to discriminate tumours accurately by their histological and geneti...

Novel mutant-enriched sequencing identified high frequency of PIK3CA mutation...

Qiu(Wanglong),Tong(Guo-Xia),Manolidis(Spir... Int J Cancer 2008-01-31

...PIK3CA are sensitive and reliable ways to detect PIK3CA mutations in clinical samples. Because PIK3CA and its pathway ar...

Amplification of PRKCI, located in 3q26, is associated with lymph node metast...

Yang(Yi-Ling),Chu(Jia-You),Luo(Man-Li),Wu(... Genes Chromosomes Cancer 2008-09-16

...PIK3CA) located on 3q26 amplification in esophageal squamous cell carcinomas (ESCCs). To assess the prevalence of copy n...

PIK3CA gene mutations and amplifications in uterine cancers, identified by me...

Miyake(Takahito),Yoshino(Kiyoshi),Enomoto(... Cancer Lett 2008-04-14

...PIK3CA gene have been frequently observed in numerous types of human malignancies. Amplification of the PIK3CA gene has ...

Anaplastic carcinoma of the thyroid arising more often from follicular carcin...

Wang(Hwei-Ming),Huang(Yu-Wen),Huang(Jen-Se... Ann Surg Oncol 2008-01-31

...PIK3CA (exons 9 and 20) and TP53 (exons 5-9), both of which have been reported in ATCs.,The results showed that approxim...

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