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Guo(C),Zhang(S),Yerramsetti(R),Zhang(J),Gu... Sci Adv 2026-05-22

...PIK3CA point mutations in cfDNA from clinical plasma samples, demonstrating high sensitivity (90.48%) and excellent spec...

Doğan(Ç),Akosman(C),Sönmez(M),Yılmaz(B),De... Mol Biol Rep 2026-05-23

...PIK3CA (14.5%). Multimetastatic patients had significantly higher cfDNA levels (10.0 ± 3.9 vs. 3.8 ± 1.0 ng; p = 0.01) a...

Wang(JW),Li(YJ),Huang(TH),Wu(HH),Wang(HH),... Biomed J 2026-05-23

...PIK3CA (16%), FGFR3 (11%), HRAS (11%)]. Notably, UC specimens with BKPyV integration harbored significantly fewer mutati...

Wang(Q),Eldfors(S),Lee(SS),Das(D),Al-Inaya... medRxiv 2026-05-14

...PIK3CA mutations, and 3q amplification, were detected exclusively in cancer, while precancers exhibited distinct HPV gen...

Huang(Z),Chen(Y),Lin(Y),Wang(Y),Li(T),Ge(X... Front Nutr None

...PIK3CA/EGFR based on computational prediction, while FSV was associated with reduced hepatic M3G levels in T2DM mice. Ho...

Yan(M),Li(X),Li(F) Transl Cancer Res 2026-04-30

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) mutations are among the most common gene...

Li(X),Katerji(M),Klapper(LM),Matikonda(S),... Res Sq 2026-05-14

...PIK3CA-altered HNSCC models. In xenografts, PAC-XL outperformed cetuximab, BGT226 and alpelisib, including complete regr...

Ono(S),Fukawa(Y),Hirose(K),Hori(Y),Motooka... Head Neck Pathol 2026-05-25

...PIK3CA (37.5%), and CASP8 (50.0%) alterations. In contrast, the SCC group showed frequent TP53 (75.0%) and CDKN2A (75.0%...

Sharma(S),Wong(HY),Johnston(RL),Koufarioti... BMC Cancer 2026-05-25

...PIK3CA, PTEN, SMARCB1 and TSC2. Candidate co-occurring alterations included co-occurrence of PTEN loss and ERBB2 amplifi...

Li(M),Guo(L),Zhao(R),Chen(S),Ma(S),Xiang(C... Curr Oncol 2026-04-29

...PIK3CA. Conclusions: CIT significantly improves initial response rates in ES-SCLC compared to CT alone. Baseline adrenal...