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TP53 BRCA1 CRISPR single-cell cancer

Kalinsky(Kevin),Jacks(Lindsay M),Heguy(Adr... Clin Cancer Res 2009-12-29

...PIK3CA mutation is identified in 32.5% of breast cancers. PIK3CA mutation significantly associates with older age at dia...

Shoji(K),Oda(K),Nakagawa(S),Hosokawa(S),Na... Br J Cancer 2009-07-08

...PIK3CA, PTEN and K-Ras.,Our results and earlier reports suggest that AKT1 mutations might be mutually exclusive with oth...

Jaiswal(Bijay S),Janakiraman(Vasantharajan... PLoS One 2009-07-20

...PIK3CA together showed efficacy.,Our data indicates that targeting oncogenic NRAS-driven melanomas require decrease in b...

Nosho(Katsuhiko),Shima(Kaori),Irahara(Nats... Clin Cancer Res 2009-07-07

...PIK3CA, and BRAF. DNMT3B expression was unrelated with patient outcome, survival, or prognosis.,Tumoral DNMT3B overexpre...

Costa(Carlota),Espinet(Blanca),Molina(Migu... Histol Histopathol 2009-08-19

...PIK3CA, hTERC, MYC, CCND1, BCL2, ZNF217 and p16) by fluorescence in situ hybridization (FISH) and/or immunohistochemistr...

Ricarte-Filho(Julio C),Ryder(Mabel),Chital... Cancer Res 2009-07-15

...PIK3CA, AKT1, and other related genes were surveyed in 31 cell lines, 52 primary tumors (34 PDTC and 18 ATC), and 55 RAI...

Ligresti(Giovanni),Militello(Loredana),Ste... Cell Cycle 2009-06-03

...PIK3CA) have been identified in a broad spectrum of tumors. Analyses of PIK3CA mutations reveals that they increase the ...

Kang(Ji Un),Koo(Sun Hoe),Kwon(Kye Chul),Pa... BMC Cancer 2009-12-11

...PIK3CA and TP73L, were observed in SCC (P < 0.05). In addition, we identified the following possible target genes (> 30%...

Boulanger(Emmanuelle),Marchio(Agnès),Hong(... Haematologica 2009-12-07

...PIK3CA, CTNNB1/beta-catenin genes and deletion of CDKN2A-ARF (p14(ARF)-p16(NK4a I) ) locus were investigated in sixteen ...

Souglakos(J),Philips(J),Wang(R),Marwah(S),... Br J Cancer 2009-08-11

We address the prognostic and predictive value of KRAS, PIK3CA and BRAF mutations for clinical outcomes in response to a...

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