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Identification of novel candidate target genes, including EPHB3, MASP1 and SS...

Kang(Ji Un),Koo(Sun Hoe),Kwon(Kye Chul),Pa... BMC Cancer 2009-12-11

...PIK3CA and TP73L, were observed in SCC (P < 0.05). In addition, we identified the following possible target genes (> 30%...

Mutational analysis of TP53, PTEN, PIK3CA and CTNNB1/beta-catenin genes in hu...

Boulanger(Emmanuelle),Marchio(Agnès),Hong(... Haematologica 2009-12-07

...PIK3CA, CTNNB1/beta-catenin genes and deletion of CDKN2A-ARF (p14(ARF)-p16(NK4a I) ) locus were investigated in sixteen ...

Relationship of CDX2 loss with molecular features and prognosis in colorectal...

Baba(Yoshifumi),Nosho(Katsuhiko),Shima(Kao... Clin Cancer Res 2009-09-28

...PIK3CA, p21, or cyclooxygenase-2. CDX2 loss was not independently associated with patient survival. However, the prognos...

Activation of phosphatidylinositol-3&#x27;-kinase/AKT signaling is essential in he...

Hartmann(Wolfgang),Küchler(Jan),Koch(Arend... Clin Cancer Res 2009-09-28

...PIK3CA, encoding a PI3K catalytic subunit, have been reported in different childhood tumors. The current study was done ...

Biomarkers predicting clinical outcome of epidermal growth factor receptor-ta...

Siena(Salvatore),Sartore-Bianchi(Andrea),D... J Natl Cancer Inst 2009-10-13

...PIK3CA oncogenes, or inactivation of the PTEN tumor suppressor gene is central to the progression of colorectal cancer. ...

PIK3CA amplification is predictive of poor prognosis in Tunisian patients wit...

Fendri(Ali),Khabir(Abdelmajid),Mnejja(Wafa... Cancer Sci 2009-11-03

...PIK3CA activation in nasopharyngeal carcinoma (NPC). This study was conducted with the aim to screen for PIK3CA mutation...

Mutation of PIK3CA: possible risk factor for cervical carcinogenesis in older...

Cui(Baoxia),Zheng(Biying),Zhang(Xi),Stenda... Int J Oncol 2009-04-27

PIK3CA encodes the p110alpha catalytic subunit of PI 3-kinase, which regulates signaling pathways important for neoplasi...

Phase I and pharmacokinetic studies of erlotinib administered concurrently wi...

Broniscer(Alberto),Baker(Suzanne J),Stewar... Clin Cancer Res 2009-07-20

...PIK3CA, and PTEN was done in tumor tissue.,Median age at diagnosis of 23 patients was 10.7 years (range, 3.7-22.5 years)...

Clonality of basal cell carcinoma arising in an epidermal nevus. New insights...

Hafner(Christian),Klein(Annette),Landthale... Dermatology 2009-06-17

...PIK3CA mutation. Further analysis suggested that this mutation is present in the basal cell carcinoma rather than in the...

Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clin...

Hildebrandt(Michelle A T),Yang(Hushan),Hun... J Clin Oncol 2009-03-31

...PIK3CA, PTEN, AKT1, AKT2, and FRAP1 (encoding mTOR) were genotyped in these patients and analyzed for associations with ...

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