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FGFR3 and PIK3CA mutations are involved in the molecular pathogenesis of sola...

Hafner(C),Stoehr(R),van Oers(J M M),Zwarth... Br J Dermatol 2009-04-22

...PIK3CA mutations have recently been identified.,To analyse SL for potential FGFR3 and PIK3CA mutations.,We screened 30 S...

Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clin...

Hildebrandt(Michelle A T),Yang(Hushan),Hun... J Clin Oncol 2009-03-31

...PIK3CA, PTEN, AKT1, AKT2, and FRAP1 (encoding mTOR) were genotyped in these patients and analyzed for associations with ...

Mutations in the phosphatidylinositol-3-kinase pathway predict for antitumor ...

Ihle(Nathan T),Lemos(Robert),Wipf(Peter),Y... Cancer Res 2009-01-30

...PIK3CA) and loss of PTEN activity were sufficient, but not necessary, as predictors of sensitivity to the antitumor acti...

Expression of activated PIK3CA in ovarian surface epithelium results in hyper...

Liang(Shun),Yang(Nuo),Pan(Yue),Deng(Shan),... PLoS One 2009-05-01

...PIK3CA, have been identified in ovarian cancer. Our in vivo data suggests that PIK3CA activation is one of the early gen...

Clinical, pathologic, and molecular features of early-onset colorectal carcin...

Yantiss(Rhonda K),Goodarzi(Mahmoud),Zhou(X... Am J Surg Pathol 2009-04-07

...PIK3CA, KRAS, and BRAF; evaluated for micro-RNA expression (miR-21, miR-20a, miR-183, miR-192, miR-145, miR-106a, miR-18...

Molecular pathology of endometrial carcinoma: practical aspects from the diag...

Llobet(D),Pallares(J),Yeramian(A),Santacan... J Clin Pathol 2009-12-07

...PIK3CA and beta-catenin genes) are characteristic of endometrioid carcinomas, whereas non-endometrioid carcinomas show a...

Frequent mutations and amplifications of the PIK3CA gene in pituitary tumors.

Lin(Yong),Jiang(Xiaofei),Shen(Ye),Li(Min),... Endocr Relat Cancer 2009-05-11

...PIK3CA gene (P<0.001), and the mutation was associated with increased disease recurrence. Genomic PIK3CA amplifications ...

Anaplastic thyroid cancer: molecular pathogenesis and emerging therapies.

Smallridge(Robert C),Marlow(Laura A),Copla... Endocr Relat Cancer 2009-05-11

...PIK3CA, TP53, AXIN1, PTEN, and APC genes, and chromosomal abnormalities are common. Several microarray studies have iden...

PIK3CA mutation occurs in nasopharyngeal carcinoma but does not significantly...

Chou(Chu-Chung),Chou(Ming-Jen),Tzen(Chin-Y... Med Oncol 2009-11-25

This study was aimed to test whether PIK3CA, BRAF and RAS are mutated in nasopharyngeal carcinomas (NPCs) and, if so, to...

Transitional cell tumors of the ovary: a comparative clinicopathologic, immun...

Cuatrecasas(Miriam),Catasus(Luis),Palacios... Am J Surg Pathol 2009-04-07

...PIK3CA, and p53 genes was also performed. The mean patient age was 58 years (range, 32 to 85 y). Abdominal enlargement a...

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