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TP53 BRCA1 CRISPR single-cell cancer

Firestein(Ron),Shima(Kaori),Nosho(Katsuhik... Int J Cancer 2010-05-06

...PIK3CA. CDK8 expression in colorectal cancer was independently associated with beta-catenin activation (p = 0.0002), fem...

Sekido(Yoshitaka) Cancer Sci 2010-03-30

...PIK3CA have been identified. Activation of multiple receptor tyrosine kinases including the epidermal growth factor rece...

Aleskandarany(Mohammed A),Rakha(Emad A),Ah... Breast Cancer Res Treat 2010-10-25

...PIK3CA protein expression in BC and to determine its association with its different molecular classes. PIK3CA protein ex...

Kataoka(Y),Mukohara(T),Shimada(H),Saijo(N)... Ann Oncol 2010-05-06

...PIK3CA-mutant cells were more resistant to CL-387,785 than PIK3CA-wild-type cells (mean percentage of control with 1 mic...

Jehan(Zeenath),Bavi(Prashant),Sultana(Meha... J Pathol 2010-02-22

...PIK3CA gains (ratio >1.0 but <2.0). Both PIK3CA amplification and gains were associated with high levels of PIK3CA prote...

Boelens(Mirjam C),Kok(Klaas),van der Vlies... Lung Cancer 2010-06-08

...PIK3CA, ADAM9, MYC and KRAS. Amplification of 2p15-p16 is a novel finding in SCC. Another novel finding is the homozygou...

McCaughan(Frank),Pole(Jessica C M),Bankier... Am J Respir Crit Care Med 2010-08-02

...PIK3CA. We confirm that both genes are amplified in all high-grade dysplastic lesions tested. We further demonstrate, in...

Mallon(Robert),Hollander(Irwin),Feldberg(L... Mol Cancer Ther 2010-07-07

...PIK3CA mutant (E545K)], 30 nmol/L PKI-402 induced cleaved poly(ADP-ribose) polymerase (PARP), a marker for apoptosis. In...

Liao(Wangjun),Liao(Yulin),Zhou(Jeff X),Xie... Anat Rec (Hoboken) 2010-09-29

Mutations of the KRAS, BRAF, and PIK3CA genes have been reported in colorectal cancer (CRC), associated with resistance ...

Irahara(Natsumi),Baba(Yoshifumi),Nosho(Kat... Diagn Mol Pathol 2010-12-06

...PIK3CA, microsatellite instability, and the CpG island methylator phenotype. Finally, we examined whether NRAS mutation ...

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