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TP53 BRCA1 CRISPR single-cell cancer

He(Youji),Van't Veer(Laura J),Mikolajewska... Clin Cancer Res 2010-03-22

...PIK3CA, KRAS, and BRAF mutations were identified in 19 (7.9%), 81 (33.9%), and 5 (2.1%) rectal cancers. Patients with PI...

Rivera(Michael),Ricarte-Filho(Julio),Patel... Hum Pathol 2010-02-19

...PIK3CA, AKT1, and other related genes. Twenty-five cases met the selection criteria. Tumor necrosis was present in 56.0%...

Troxell(Megan L),Levine(Judith),Beadling(C... Mod Pathol 2010-03-03

...PIK3CA (exon 20 >exon 9, 27 cases). Papillomas had more mutations in AKT1 (54%) than in PIK3CA (21%), whereas papillomas...

Sartore-Bianchi(Andrea),Di Nicolantonio(Fe... PLoS One 2010-03-12

...PIK3CA/PTEN pathway have independently been found to give rise to resistance. We present a comprehensive analysis of KRA...

Li(Hua),Zhu(Rong),Wang(Lei),Zhu(Tengfang),... Exp Mol Pathol 2010-02-25

...PIK3CA are found in 20% to 40% of invasive breast cancers. To investigate the frequency of PIK3CA mutations in the intra...

Soh(Junichi),Okumura(Naoki),Lockwood(Willi... PLoS One 2010-03-12

...PIK3CA and EGFR genes by direct sequencing and quantitative PCR assay in over 400 human tumors, cell lines, and xenograf...

Huang(Huang),Qiao(Renping),Zhao(Deyao),Zha... Nucleic Acids Res 2010-02-12

...PIK3CA gene at two SNP sites. Furthermore, conformational distortion of siRNA-target duplex was observed to correlate wi...

López-Knowles(Elena),Zardawi(Sarah J),McNe... Cancer Epidemiol Biomarkers... 2010-03-09

...PIK3CA mutations (P = 0.05) or PTEN loss (P = 0.05). Low cytoplasmic expression (high MTC score) was associated with the...

Varella-Garcia(Marileila) Cell Adh Migr 2010-09-09

...PIK3CA, NKX2-1 and ALK; tumor suppressor genes include TP53, RB1, CDKN2, and a cluster of genes mapped at 3p. MicroRNA r...

Fadhil(Wakkas),Ibrahem(Salih),Seth(Rashmi)... J Clin Pathol 2010-06-17

...PIK3CA and CDC4 were screened in 29 cell lines with 100% sensitivity and specificity. Forty-three FFPE colorectal tumour...

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