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Genomic characterization of gene copy-number aberrations in endometrial carci...

Wang(Yingmei),Yang(Da),Cogdell(David),Hu(L... Technol Cancer Res Treat 2010-06-14

...PIK3CA (3q26.3), K-ras (12p12.1), R-ras (19q13.3-qter), Raf-1 (3p25), EGFR (7p12), Akt1 (14q32.32), and Akt2 (19q13.1-q1...

Chromosomal imbalances are uncommon in chagasic megaesophagus.

Bellini(Marilanda F),Manzato(Antonio J),Si... BMC Gastroenterol 2010-06-24

...PIK3CA, EGFR, CDKN2A, YES and gains at PIK3CA, TP63, FGFR1, MYC, CDNK2A and NCOA3 were detected in few CM cases, mainly ...

Expression profiling of 22 genes involved in the PI3K-AKT pathway identifies ...

Catasus(Lluis),D'Angelo(Emanuela),Pons(Cri... Mod Pathol 2010-07-26

...PIK3CA mutations (2/6; 33%). Exon 20 PIK3CA and PTEN mutations were not found in this subgroup. Low-grade endometrial ca...

Progressive 3q amplification consistently targets SOX2 in preinvasive squamou...

McCaughan(Frank),Pole(Jessica C M),Bankier... Am J Respir Crit Care Med 2010-08-02

...PIK3CA. We confirm that both genes are amplified in all high-grade dysplastic lesions tested. We further demonstrate, in...

MEK1 and AKT2 mutations in Japanese lung cancer.

Sasaki(Hidefumi),Hikosaka(Yu),Kawano(Osamu... J Thorac Oncol 2010-08-12

...PIK3CA mutations.,This study demonstrated that mutation in the kinase domain of AKT2 and MEK1 exon 2 mutation occurred i...

Prognostic significance of AMP-activated protein kinase expression and modify...

Baba(Y),Nosho(K),Shima(K),Meyerhardt(J A),... Br J Cancer 2010-10-25

...PIK3CA mutations.,Phosphorylated AMPK expression was not associated with survival among all patients. Notably, prognosti...

Randomized, phase II study of the insulin-like growth factor-1 receptor inhib...

Reidy(Diane Lauren),Vakiani(Efsevia),Fakih... J Clin Oncol 2010-10-18

...PIK3CA, and BRAF genotyping, and immunohistochemistry was obtained for pAKT as well as IGF-1R.,Overall, 64 patients were...

Benign serrated colorectal fibroblastic polyps/intramucosal perineuriomas are...

Agaimy(Abbas),Stoehr(Robert),Vieth(Michael... Am J Surg Pathol 2010-11-15

...PIK3CA). Patients were 23 women and 6 men with a mean age of 64 years (range: 47 to 84 y). All lesions represented asymp...

Detection of PIK3CA mutations in circulating free DNA in patients with breast...

Board(Ruth E),Wardley(Andrew M),Dixon(J Mi... Breast Cancer Res Treat 2010-06-16

...PIK3CA mutations using Amplification Refractory Mutation System (ARMS()) allele-specific PCR and Scorpion probes. PIK3CA...

Molecular alterations in uterine serous carcinoma.

Hayes(Monica Prasad),Ellenson(Lora Hedrick... Gynecol Oncol 2010-02-05

...PIK3CA, which encodes the catalytic p110-alpha subunit of phosphatidylinositol 3-kinase (PI3K). In addition, claudin-3 a...

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