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TP53 BRCA1 CRISPR single-cell cancer

Hägerstrand(Daniel),Lindh(Maja Bradic),Peñ... Neuro Oncol 2010-12-02

...PIK3CA were found in 2 cultures, and 2 other cultures displayed ligand-independent Akt phosphorylation. Growth inhibitio...

Sartore-Bianchi(Andrea),Bencardino(Katia),... Target Oncol 2010-09-22

...PIK3CA/PTEN alterations could also be useful for selecting patients with reduced chance to benefit from EGFR-targeted th...

Lièvre(A),Blons(H),Laurent-Puig(P) Oncogene 2010-07-07

...PIK3CA mutations or loss of PTEN expression, may also be additional interesting predictive markers of response to anti-E...

Boormans(J L),Korsten(H),Ziel-van der Made... Br J Cancer 2010-06-09

...PIK3CA and PIK3R1 was carried out in samples from primary and recurrent prostate tumours.,We show that, in prostate canc...

Kostakis(George C),Papadogeorgakis(Nikos),... Oral Surg Oral Med Oral Pat... 2010-07-16

...PIK3CA) gene, which encodes for one of these kinases, in several human solid tumors, including oral squamous cell carcin...

Wang(Yingmei),Yang(Da),Cogdell(David),Hu(L... Technol Cancer Res Treat 2010-06-14

...PIK3CA (3q26.3), K-ras (12p12.1), R-ras (19q13.3-qter), Raf-1 (3p25), EGFR (7p12), Akt1 (14q32.32), and Akt2 (19q13.1-q1...

Fumagalli(Debora),Gavin(Patrick G),Taniyam... BMC Cancer 2010-04-12

...PIK3CA, and 12.1% for BRAF. In addition, infrequent mutations in NRAS, AKT1, ABL1, and MET were detected. Mutation profi...

Kuo(Kuan-Ting),Mao(Tsui-Lien),Chen(Xu),Fen... Clin Cancer Res 2010-08-06

...PIK3CA. The purpose of this study is to comprehensively define the genomic changes in CCC based on DNA copy number alter...

Sartore-Bianchi(Andrea),Di Nicolantonio(Fe... PLoS One 2010-03-12

...PIK3CA/PTEN pathway have independently been found to give rise to resistance. We present a comprehensive analysis of KRA...

Kong(Dexin),Yamori(Takao) Curr Med Chem 2010-02-04

...PIK3CA encoding PI3Kalpha, as well as loss-of-function mutations of PTEN, have been frequently found in human cancers. T...

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