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Al-Qahtani(MH),Jafri(MA),Assidi(M),Buhmeid... Sci Rep 2026-06-18

...PIK3CA (PDB ID: 7R9V)-are pivotal in tumour progression and resistance mechanisms. Targeting these proteins using multit...

Monserrat(L),García-García(J),Molina(C),Òd... NPJ Breast Cancer 2026-06-17

...PIK3CA, or PTEN mutations. Tumors sensitive to SARMs were enriched in GATA3 mutations. EP0062 treatment induced AR-targe...

Cheng(J),He(Y),Yuan(Y),Mu(Y),Zhao(X),Wu(F)... Environ Sci Technol 2026-06-30

...PIK3CA (18.06%), with some LCMs exhibiting docking energies comparable to known inhibitors. Structural analysis identifi...

Guo(Y),Wu(X),Liang(P),Li(X),Zhou(W),Wu(Z),... Curr Pharm Des 2026-06-16

...PIK3CA, Bcl2, and HIF-1α among the core targets. The stable binding of GCM to these targets was predicted using molecula...

Alorjani(MS),Sobrinho-Simões(M),Al-Oqaily(... Virchows Arch 2026-06-19

...PIK3CA, KMT2C, KMT2D, TERT promoter or RET rearrangements. BRAF mutations do not occur. We describe a sporadic case of h...

Li(Y),Li(S),Li(Y),Pan(Z) Drug Des Devel Ther None

...PIK3CA, CDKN2A, PTEN, and FGF/FGFR pathways. PI3K pathway alterations were not associated with prolonged PFS. Tumors wit...

de Brito Vieira Neto(J),Moraes de Farias(K... Front Pharmacol None

...PIK3CA, ARID4B, and COL16A1, are linked to microtubule dynamics and cell cycle regulation; the main downregulated, namel...

Roncarati(R),Fontana(B),Pace(I),Durante(G)... Front Med (Lausanne) None

...PIK3CA. Mutated genes were primarily involved in cell-cycle regulation, receptor tyrosine kinase signaling, and NOTCH pa...

Verma(N),Singh(V) Ann Afr Med 2026-06-19

...PIK3CA and TP53) and methylation profiling (e.g. CADM1 and PAX1) show utility for molecular characterization and resista...

Tan(SH),Subramaniam(S),Lai(WH),Razali(F),T... Discov Oncol 2026-06-19

...PIK3CA, and CDKN2A were identified, alongside mismatch repair deficiency and microsatellite instability in colorectal an...