主页文献库搜索
A novel PIK3CA hotspot mutation in Isfahanian breast cancer patients.

Gharbi(Sedigheh),Faghihi(Mehri),Tavassoli(... Cancer Invest 2011-05-27

...PIK3CA) play an important role in tumorigenesis. Using PCR-SSCP, followed by sequencing, we examined the PIK3CA gene ove...

Luminal expression of PIK3CA mutant H1047R in the mammary gland induces heter...

Meyer(Dominique S),Brinkhaus(Heike),Müller... Cancer Res 2011-09-29

...PIK3CA, which encodes the α-catalytic subunit of PI3K, occur in approximately 30% of breast cancers. These mutations res...

Roles of BIM induction and survivin downregulation in lapatinib-induced apopt...

Tanizaki(J),Okamoto(I),Fumita(S),Okamoto(W... Oncogene 2011-12-07

...PIK3CA mutation than in those without one. Lapatinib failed to inhibit AKT phosphorylation in PIK3CA mutant cells, likel...

Genotypic and histological evolution of lung cancers acquiring resistance to ...

Sequist(Lecia V),Waltman(Belinda A),Dias-S... Sci Transl Med 2011-07-14

...PIK3CA gene, whereas others underwent a pronounced epithelial-to-mesenchymal transition. Surprisingly, five resistant tu...

PIK3CA mutations and amplification in endometrioid endometrial carcinomas: re...

Konopka(Bożena),Janiec-Jankowska(Aneta),Kw... Hum Pathol 2011-12-05

...PIK3CA mutations were found in 39 (20%) carcinomas. Six new mutations were identified. No PIK3CA mutations were found in...

The selective class I PI3K inhibitor CH5132799 targets human cancers harborin...

Tanaka(Hiroshi),Yoshida(Miyuki),Tanimura(H... Clin Cancer Res 2011-10-07

...PIK3CA mutations. Prediction of CH5132799 response on the basis of PIK3CA mutations could enable patient stratification ...

Histologic, molecular, and cytogenetic features of ovarian cancers: implicati...

Lalwani(Neeraj),Prasad(Srinivasa R),Vikram... Radiographics 2011-09-22

...PIK3CA genes, respectively. High-grade serous carcinomas, the most common subtype, often manifest with early transcoelom...

Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway-depe...

Liu(Pixu),Cheng(Hailing),Santiago(Stephani... Nat Med 2011-11-18

...PIK3CA(H1047R). Notably, most PIK3CA(H1047R)-driven mammary tumors recurred after PIK3CA(H1047R) inactivation. Genomic a...

Selective gene expression profiling of mTOR-associated tumor suppressor and o...

Laudański(Piotr),Kowalczuk(Oksana),Klasa-M... Folia Histochem Cytobiol 2011-10-27

...PIK3CA and BECN1. Confirmatory immunohistochemical detection was performed for a group of selected proteins. Particularl...

AKT1(E17K) in human solid tumours.

Bleeker(F E),Felicioni(L),Buttitta(F),Lamb... Oncogene 2010-07-09

...PIK3CA(E454K or H1047R) alleles and was present only in ductal and lobular histotypes. Our results, showing that AKT1 mu...

上一页 254 255 256 257 258 259 260 261 262 下一页 258 / 共 350

联系地址

山东省济南市章丘区文博路2号

齐鲁师范学院 genelibs生信实验室

山东省济南市高新区舜华路750号

大学科技园北区F座4单元2楼

电话: 0531-88819269

微信公众号

关注微信订阅号,实时查看信息,关注医学生物学动态。


商务邮箱

E-mail: product@genelibs.com