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TP53 BRCA1 CRISPR single-cell cancer

Hinoda(Yuji) Rinsho Byori 2011-10-25

...PIK3CA mutations, PTEN down-regulation and EGFR gene amplification on the efficacy of anti-EGFR antibodies in CRC patien...

Nguyen(Quang-Dé),Perumal(Meg),Waldman(Todd... Transl Oncol 2011-11-10

...PIK3CA, PTEN, and AKT genes frequently found in a broad range of cancers. Given its role in glucose metabolism, we inves...

Lin(Jennifer S),Webber(Elizabeth M),Senger... Am J Cancer Res 2011-11-10

...PIK3CA, eight that studied PTEN expression, and five that studied AKT expression. The best evidence for BRAF, NRAS, and ...

Soeda(Hiroshi),Shimodaira(Hideki),Ishioka(... Gan To Kagaku Ryoho 2011-08-05

...PIK3CA, PTENgenes. Cetuximab, a chimeric immunoglobulin 1 (IgG1) monoclonal antibody, may also exert antitumor effects t...

Oda(Katsutoshi) Gan To Kagaku Ryoho 2011-08-05

...PIK3CA (30%), and K-Ras (20%), are frequently observed in endometrial cancer. A coexistence of these mutations is also c...

Yang(Xuemei),Turke(Alexa B),Qi(Jie),Song(Y... Cancer Res 2011-11-23

...PIK3CA, where tandem mass spectrometry detected and quantitatively measured the abundance of a helical domain mutant (E5...

Liu(Pixu),Cheng(Hailing),Santiago(Stephani... Nat Med 2011-11-18

...PIK3CA(H1047R). Notably, most PIK3CA(H1047R)-driven mammary tumors recurred after PIK3CA(H1047R) inactivation. Genomic a...

Janku(Filip),Lee(J Jack),Tsimberidou(Apost... PLoS One 2011-12-06

...PIK3CA mutations vs. 24% of patients wtPIK3CA (p = 0.001). PIK3CA mutations were found in 28% of patients with KRAS muta...

Ilic(Nina),Utermark(Tamara),Widlund(Hans R... Proc Natl Acad Sci U S A 2011-11-09

...PIK3CA. Although targeted inhibition of a cancer survival gene holds significant promise, there are concerns that drug r...

Oikonomou(Eftychia),Koc(Michal),Sourkova(V... PLoS One 2011-12-01

...PIK3CAH1047) cells. In contrast, for the same level of apoptosis in HT29(BRAFV600E/PIK3CAP449T) cells, TRAIL was combine...

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